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Apoptosis regulator Bcl-2 antibody

Antigen

Apoptosis regulator Bcl-2

Clonality Monoclonal (4C10-E4-C7)
Host

Mouse

Reactivity

Human

Application
ELISA, Western Blotting (WB)
Catalog no. ABIN488235
Quantity 100µg  (1. 000mg/ml)
Price 497.14 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information

Gene ID BCL2
Swiss-Prot P10415
Immunogen A synthetic peptide, CGGGITLGAYLGHK, corresponding to C terminal amino acids 229aa-239aa of human BCL2.
Format Purified
Isotype IgG1  (Matching secondary antibodies)
Clone 4C10-E4-C7
Description This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. Caution hazardous ingredient: Sodium azide, avoid exposure to skin and eyes, ingestion, and contact with heat, acids, and metals or metal ions. Wash exposed skin with soap and water. Flush eyes with water. Do not discard into plumbing.
Specificity Mouse monoclonal to BCL2

Application Details

Application Notes ELISA: 1/5000 – 1/20000. WB: 1/100-1/2000
Concentration 1. 000mg/ml
Purity > 90%
Purification Protein G-Sepharose affinity purified
Buffer Preservative: 0. 02% Sodium Azide and 50% glycerol, 1% BSA, PBS, PH7. 4.
Storage Store at -20°C. Avoid repeated freeze / thaw cycles. Ship at 4°-10°
Research Area Cancer, Metabolism, Apoptosis/Necrosis, Bacteria
Restrictions For Research Use only