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beta-Catenin (CTNNB1) antibody

Antigen

beta-Catenin (CTNNB1)
Synonyms
CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1) ... show more
Clonality Monoclonal (3B12-A12-E3)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Application
Alternatives ELISA, Western Blotting (WB)
Catalog no. ABIN488242
Quantity 100µg  (1. 000mg/ml)
Price 497.14 $   Plus shipping costs $35.00
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anti-beta-Catenin (CTNNB1) antibody

Additional Information
Application Details Images Alternatives Secondary Antibodies back to top

Alternative name Catenin beta-1
Gene ID CTNNB1
Swiss-Prot P35222
Immunogen A synthetic peptide (CGGGAPSLSGKGNPEEEDVDTS) of human CTNNB1 (N-terminus).
Format Purified
Isotype IgG1  (Matching secondary antibodies)
Clone 3B12-A12-E3
Description The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Caution hazardous ingredient: Sodium azide, avoid exposure to skin and eyes, ingestion, and contact with heat, acids, and metals or metal ions. Wash exposed skin with soap and water. Flush eyes with water. Do not discard into plumbing.
Specificity Mouse monoclonal to CTNNB1
Synonyms CTNNB, FLJ25606, FLJ37923, DKFZp686D02253, Mesc, Catnb, ctnnb, id:ibd2058, wu:fb73e10, wu:fi81c06, wu:fk25h01, ARM, Beta-cat, Beta-catenin, EG:86E4.6, beta-cat-arm, l(1)2Bv, l(1)G0192, l(1)G0234, l(1)G0410, l(1)arm, t12687 ALR Dm, DmelCG11579, CG11579, beta-catenin, ctnnb1, MGC79992, MGC132060, Cibeta-catenin, CTNNB1, MGC52601, LOC576711, Ctnnb1, MGC139922

Application Details
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Application Notes ELISA: 1/5000 – 1/20000. WB: 1/100-1/2000
Concentration 1. 000mg/ml
Purity > 90%
Purification Protein G-Sepharose affinity purified
Buffer Preservative: 0. 02% Sodium Azide and 50% glycerol, 1% BSA, PBS, PH7. 4.
Storage Store at -20°C. Avoid repeated freeze / thaw cycles. Ship at 4°-10°
Research Area Cardiovascular, Atherosclerosis, Inflammation, Cancer, Bacteria, Extracellular Matrix, Cell Structure, Stem Cells, Signaling, Neurogenesis, Cytoskeleton, Microfilaments
Restrictions For Research Use only

Alternatives
Application Details Images Secondary Antibodies back to top

Alternatives for antigen "beta-Catenin (CTNNB1)", type "Antibodies"
Hosts Rabbit (149), Mouse (41)
Reactivities Human (173), Mouse (Murine) (114), Rat (Rattus) (105), Chicken (18), Dog (Canine) (6), Hamster (2), Xenopus laevis (2), Monkey (1)
Applications Western Blotting (WB) (169), Immunofluorescence (IF) (56), Immunoprecipitation (IP) (47), Enzyme Immunoassay (EIA) (43), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (43), Immunohistochemistry (IHC) (36), ELISA (26), Flow Cytometry (FACS) (18), Immunohistochemistry (Frozen Sections) (IHC (fro)) (12), Dot Blot (Dot) (7), Immunocytochemistry (ICC) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunoelectron Microscopy (IEM) (1)
Conjugates Biotin (5), FITC (2), HRP (2), Alexa Flour 488 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), Gold (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy7 (1), RBITC (1)
Epitopes pSer37 (9), pSer33 (8), Ab-33 (5), Ab-37 (5), Ab-41/45 (5), C-Term (5), pThr41/Ser45 (5), pThr41/pSer45 (4), Ab-654 (3), pTyr654 (3), pTyr86 (3), exon 3 (2), pSer33/37 (2), Ab-489 (1), Core (1), dep27-37 (1), dep35-50 (1), pSer45 (1), pTyr489 (1)