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Glycogen synthase kinase-3 beta antibody

Antigen

Glycogen synthase kinase-3 beta

Clonality Monoclonal (1E7-F3-G8)
Host

Mouse

Reactivity

Human

Application
ELISA, Western Blotting (WB)
Catalog no. ABIN488257
Quantity 100µg  (1. 000mg/ml)
Price 497.14 $   Plus shipping costs $35.00
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Availability Ships within 5 to 7 Business Days

Additional Information

Gene ID GSK3B
Swiss-Prot P49841
Immunogen Recombinant fragment, corresponding to amino acids 313-422AA of human GSK3B(C-terminus).
Format Purified
Isotype IgG1  (Matching secondary antibodies)
Clone 1E7-F3-G8
Description The protein encoded by this gene is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It is involved in energy metabolism, neuronal cell development, and body pattern formation. Polymorphisms in this gene have been implicated in modifying risk of Parkinson disease, and studies in mice show that overexpression of this gene may be relevant to the pathogenesis of Alzheimer disease. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. Caution hazardous ingredient: Sodium azide, avoid exposure to skin and eyes, ingestion, and contact with heat, acids, and metals or metal ions. Wash exposed skin with soap and water. Flush eyes with water. Do not discard into plumbing.
Specificity Mouse monoclonal to GSK3B

Application Details

Application Notes ELISA: 1/5000 – 1/20000. WB: 1/100-1/2000
Concentration 1. 000mg/ml
Purity > 90%
Purification Protein G-Sepharose affinity purified
Buffer Preservative: 0. 02% Sodium Azide and 50% glycerol, 1% BSA, PBS, PH7. 4.
Storage Store at -20°C. Avoid repeated freeze / thaw cycles. Ship at 4°-10°
Research Area Cancer, Signaling, Metabolism, Cardiovascular, Organogenesis, Hypertrophy, Atherosclerosis, Diabetes, Stem Cells, Cell Signaling, Cytoplasmatic Domain, Protein Modifications, Kinases/Phosphatases, Neurogenesis
Restrictions For Research Use only