ADAMTS13 antibody (AA 299-488)

Catalog No. ABIN4886425

Product Details anti-ADAMTS13 Antibody

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Binding Specificity: AA 299-488

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADAMTS13 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 13(ADAMTS13) detection. Tested with WB, ELISA in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 13(ADAMTS13) detection. Tested with WB, ELISA in Human,Mouse,Rat.
Gene Name: ADAM metallopeptidase with thrombospondin type 1 motif 13
Protein Name: A disintegrin and metalloproteinase with thrombospondin motifs 13

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ADAMTS13 recombinant protein (Position: A299-R488). Human ADAMTS13 shares 85.2% amino acid (aa) sequence identity with mouse ADAMTS13.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ADAMTS13

Target: ADAMTS13 (ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))

Alternative Name: ADAMTS13 (ADAMTS13 Products)

Synonyms: ADAMTS13 antibody, ADAM-TS13 antibody, ADAMTS-13 antibody, C9orf8 antibody, VWFCP antibody, vWF-CP antibody, Gm710 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 13 antibody, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 antibody, ADAM metallopeptidase with thrombospondin type 1 motif, 13 antibody, ADAMTS13 antibody, Adamts13 antibody, adamts13 antibody

Background: ADAMTS13 (a disintegrin and metalloproteinase with athrombospondin type 1 motif, member 13), also known as VWFCP, is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. This gene is mapped to 9q34.

Synonyms: ADAM TS | ADAM-TS 13 | ADAM-TS13 | ADAMTS 13 | ADAMTS-13 | ADAMTS13 | C9orf8 | TTP | vWF CP | vWF-CP | vWFCP | Q76LX8

Gene ID: 11093