ADK antibody (AA 165-351)

Catalog No. ABIN4886430

Product Details anti-ADK Antibody

Target: ADK (Adenosine Kinase (ADK))

Binding Specificity: AA 165-351

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADK antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for Adenosine kinase(ADK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Adenosine kinase(ADK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: adenosine kinase
Protein Name: Adenosine kinase

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human ADK recombinant protein (Position: K165-T351). Human ADK shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat ADK, respectively.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ADK

Target: ADK (Adenosine Kinase (ADK))

Alternative Name: ADK (ADK Products)

Synonyms: AK antibody, ADK antibody, DDBDRAFT_0186795 antibody, DDBDRAFT_0230174 antibody, DDB_0186795 antibody, DDB_0230174 antibody, ATPADK1 antibody, F3G5.4 antibody, F3G5_4 antibody, adenosine kinase antibody, adk antibody, 2310026J05Rik antibody, 5033405D03Rik antibody, AI255373 antibody, AI987814 antibody, Ak antibody, adenosine kinase antibody, ATP:adenosine 5'-phosphotransferase antibody, Adenosine kinase antibody, adenosine kinase S homeolog antibody, ADK antibody, adk antibody, Adk antibody, CNN02130 antibody, LOC5572668 antibody, CMU_026370 antibody, adk.S antibody

Background: This gene is an enzyme which catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Multiple transcript variants encoding different isoforms have been found for this gene.

Synonyms: Adenosine 5''-phosphotransferase | Adenosine kinase | adk | AK | P55263

Gene ID: 132

UniProt: P55263

Pathways: Ribonucleoside Biosynthetic Process