GLRX3 antibody (AA 89-177)
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- Target See all GLRX3 Antibodies
- GLRX3 (Glutaredoxin 3 (GLRX3))
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Binding Specificity
- AA 89-177
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GLRX3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Purpose
- Rabbit IgG polyclonal antibody for Glutaredoxin-3(GLRX3) detection. Tested with WB in Human,Mouse,Rat.
- Cross-Reactivity (Details)
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Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Characteristics
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Rabbit IgG polyclonal antibody for Glutaredoxin-3(GLRX3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: glutaredoxin 3
Protein Name: Glutaredoxin-3 - Purification
- Immunogen affinity purified.
- Immunogen
- E. coli-derived human TXNL2 recombinant protein (Position: L89-S177). Human TXNL2 shares 93.3% and 94.4% amino acid (aa) sequence identity with mouse and rat TXNL2, respectively.
- Isotype
- IgG
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- Application Notes
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users. - Comment
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Target
- GLRX3 (Glutaredoxin 3 (GLRX3))
- Alternative Name
- GLRX3 (GLRX3 Products)
- Synonyms
- GLRX4 antibody, GRX3 antibody, GRX4 antibody, PICOT antibody, TXNL2 antibody, TXNL3 antibody, Txnl2 antibody, txnl2 antibody, wu:fb38e09 antibody, zgc:103648 antibody, NME/NM23 family member 9 antibody, thioredoxin-like 2 antibody, glutaredoxin 3 antibody, NME9 antibody, LOC100285323 antibody, GLRX3 antibody, Glrx3 antibody, glrx3 antibody
- Background
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Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.
Synonyms: glrx3 | GLRX4 | Glutaredoxin 3 | Glutaredoxin 4 | Glutaredoxin-3 | GRX3 | GRX4 | PICOT | TXNL3 | O76003 - Gene ID
- 10539
- UniProt
- O76003
- Pathways
- Cell RedoxHomeostasis
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