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PVRL4 antibody (N-Term)

PVRL4 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN4886678
  • Target See all PVRL4 Antibodies
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    Binding Specificity
    • 8
    • 7
    • 6
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 53-94, N-Term
    Reactivity
    • 48
    • 22
    • 14
    Human
    Host
    • 43
    • 5
    • 2
    Rabbit
    Clonality
    • 44
    • 5
    • 1
    Polyclonal
    Conjugate
    • 23
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PVRL4 antibody is un-conjugated
    Application
    • 46
    • 28
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Nectin-4(NECTIN4) detection. Tested with WB in Human.
    Sequence
    FYRGDSGEQV GQVAWARVDA GEGAQELALL HSKYGL
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Nectin-4(NECTIN4) detection. Tested with WB in Human.
    Gene Name: nectin cell adhesion molecule 4
    Protein Name: Nectin-4
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human Nectin-4/PVRL4 (53-94aa FYRGDSGEQVGQVAWARVDAGEGAQELALLHSKYGL HVSPAY), different from the related mouse sequence by seven amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product PVRL4 Primary Antibody
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
    Alternative Name
    NECTIN4 (PVRL4 Products)
    Synonyms
    PVRL4 antibody, si:ch211-155e24.1 antibody, 1200017F15Rik antibody, Prr4 antibody, RGD1559826 antibody, EDSS1 antibody, LNIR antibody, PRR4 antibody, nectin-4 antibody, nectin cell adhesion molecule 4 antibody, NECTIN4 antibody, nectin4 antibody, Nectin4 antibody
    Background
    PVRL4, also known as Nectin-4, is expressed in human skin, hair follicles, and cultured keratinocytes, but not in fibroblasts. This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.

    Synonyms: EDSS1 | Nectin 4 | Nectin-4 | PRR4 | pvrl4 | Q96NY8
    Gene ID
    81607
    Pathways
    Cell-Cell Junction Organization
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