Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A) antibody (RPE)

Antigen: Tumor Necrosis Factor Receptor Superfamily, Member 1A (TNFRSF1A)

Synonyms: FPF, p55, p60, TBP1, TNF-R, TNFAR, TNFR1, p55-R, CD120a, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC19588, fpf, tbp1, p55-r, tnf-r, tnfar, tnfr1, cd120a, tnfr55, tnfr60, xtnfr1, zgc:85914, wu:fj65b10, TNFRSF1A, TNFR I, TNFRI, Tnfr1, TNF-R1, Tnfr-2, TNFRp55, TNF-alphaR1, TNFalpha-R1

Clonality: Monoclonal (55R-286)

Host: Armenian Hamster

Reactivity: Mouse (Murine)

Conjugate: RPE

Catalog no.: ABIN488688

Additional Information

Alternative name: CD120Alpha

Isotype: IgG

Clone: 55R-286

Description: Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-a and TNF- (also known as LT-a). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-?B induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.

Specificity: Armenian Hamster Anti-Mouse CD120a (Clone 55R-286) recognizes Mouse CD120a. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Synonyms: FPF, p55, p60, TBP1, TNF-R, TNFAR, TNFR1, p55-R, CD120a, TNFR55, TNFR60, TNF-R-I, TNF-R55, MGC19588, fpf, tbp1, p55-r, tnf-r, tnfar, tnfr1, cd120a, tnfr55, tnfr60, xtnfr1, zgc:85914, wu:fj65b10, TNFRSF1A, TNFR I, TNFRI, Tnfr1, TNF-R1, Tnfr-2, TNFRp55, TNF-alphaR1, TNFalpha-R1

Application Details

Concentration: 0.1 mg/ml

Buffer: This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability. Endotoxin: Functional.

Storage: This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.

Restrictions: For Research Use only