Interferon, beta 1, Fibroblast (IFNB1) antibody

Antigen: Interferon, beta 1, Fibroblast (IFNB1)

Synonyms: IFB, IFF, IFNB, MGC96956, Ifb, IFN-beta, Ifnb, IFNB1, IFNb

Clonality: Monoclonal (MIB-5E9-1)

Host: Armenian Hamster

Reactivity: Mouse (Murine)

Application: Western Blotting (WB), Immunoprecipitation (IP)

Catalog no.: ABIN488694

Additional Information

Alternative name: IFNbeta

Isotype: IgG  (Matching secondary antibodies)

Clone: MIB-5E9-1

Description: Interferons (IFN) consist of two classes. The type I IFN class consists of 20 highly similar IFN-a proteins and a single IFN- protein. The second class, type II IFN, consists of a single protein, IFN-?. IFN-a and IFN- signal through the same cell surface receptor IFNAR1 and have a similar range of biological activities including antiviral and antiproliferative activity. The type I IFNs also influence activation, growth and differentiation of T cells, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. IFN- has recently proven to be beneficial in patients with multiple sclerosis and could also be a potential therapy for rheumatoid arthritis. It is unclear what cellular mechanisms are involved in IFN-ߒs therapeutic effects, but they may be caused by a restoration of balance between pro- and anti-inflammatory cytokines.

Specificity: Armenian Hamster Anti-Mouse IFN (Clone MIB-5E9.1) recognizes Mouse IFN. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Application Details

Application Notes: IP, WB. Each Investigator should determine their own optimal working dilution for specific applications.

Concentration: 0.1 mg/ml

Purification: Purified

Buffer: This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability This antibody is stable for at least one week when stored at 2-8C. For long term sto

Storage: This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.

Restrictions: For Research Use only