IL-1 R1 antibody (Biotin)
| Antigen |
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| Clonality |
Monoclonal (JAMA-147) |
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Host
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Reactivity
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Conjugate
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| Catalog no. |
ABIN488768 |
| Quantity |
50 µg (0.1 mg/ml) |
| Price |
75.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 3 to 10 Business Days |
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Isotype
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IgG
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Clone
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JAMA-147
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Description
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IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1a and IL-1 exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1a and IL-1, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
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Specificity
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Armenian Hamster Anti-Mouse IL-1 R1 (Clone JAMA-147) recognizes Mouse IL-1 R1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
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Concentration
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0.1 mg/ml
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Buffer
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This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability. Endotoxin: Functional.
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Storage
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This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
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Restrictions
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For Research Use only
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Alternatives for antigen "IL-1 R1", type "Antibodies"
Alternatives 
