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Details for Product No. ABIN488806

Tumor Necrosis Factor (TNF) antibody

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Antigen
Synonyms DIF, TNFA, TNFSF2, TNF-alpha, RATTNF, Tnfa, TNF-a, TNFalpha, Tnfsf1a, TNFa, cTNF, TNF-ALPHA, zgc:55302, wu:fi06b02, TNFAIP1, TNF, tnf, Tnf-alpha, tnfa-like, dif, tnfa, xtnf, tnfsf2, tnf-alpha
Reactivity
»Alternatives Mouse (Murine)
Host
»Alternatives Armenian Hamster
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Flow Cytometry (FACS), Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN488806
Quantity 100 µg
Price
143.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Clone TN3-19-12
Isotype IgG
Specificity Armenian Hamster Anti-Mouse TNFa (Clone TN3-19.12) recognizes Mouse TNFa. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Purification Purified
Alternative Name TNF-Alpha
Background The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity.1 It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites.2 TNF-a is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-a secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-a has been detected in synovial fluid of patients with rheumatoid arthritis.
Application Notes FC, WB. Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Concentration 0.1 mg/ml
Buffer This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability This antibody is stable for at least one week when stored at 2-8C. For long term sto
Preservative Sodium azide
Storage 4 °C
Product cited in: Taylor, Wilkison, Voyich et al.: "Prevention of bone marrow cell apoptosis and regulation of hematopoiesis by type I IFNs during systemic responses to pneumocystis lung infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 5956-67, 2011 (PubMed). Further details: Anti

Ermann, Garrett, Kuchroo et al.: "Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 17, pp. 7137-41, 2011 (PubMed).

Alternatives for antigen "Tumor Necrosis Factor (TNF)", type "Antibodies"
Hosts (338), (262), (109), (29), (13), (8), (6), (4), (1)
Reactivities (501), (200), (97), (72), (57), (29), (27), (22), (9), (8), (7), (6), (6), (6), (2), (1), (1), (1), (1), (1)
Applications (448), (396), (207), (102), (102), (71), (61), (57), (46), (43), (39), (32), (29), (21), (20), (15), (14), (7), (6), (5), (5), (3), (3), (3), (3), (2), (1), (1), (1)
Conjugates (95), (47), (23), (8), (7), (6), (6), (5), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (11), (7), (5), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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