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Tumor Necrosis Factor (TNF) antibody
| Antigen | Tumor Necrosis Factor (TNF) |
| Synonyms |
DIF, TNFA, TNFSF2, TNF-alpha, B12, B61, EDP1, MGC2317, Edp1, Edp-1, Tnfip1, Tnfa, RATTNF, MGC124630, zgc:55302, wu:fi06b02, TNFAIP1, TNF, tnf, DKFZp468A2328, Tnfsf1a, TNFalpha, MGC151434, TNFa, cTNF, ...
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| Clonality | Monoclonal (TN3-19-12) |
| Host |
 Alternatives Armenian Hamster |
| Reactivity |
Alternatives Mouse (Murine) |
| Conjugate |
Alternatives Un-conjugated |
| Application |
Alternatives Flow Cytometry (FACS), Western Blotting (WB) |
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2 references available |
| Catalog no. | ABIN488806 |
| Quantity | 100µg (0.1 mg/ml) |
| Price | 143.00 $ Plus shipping costs $45.00 |
| Shipping to |
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| Availability | Will be delivered in 2 to 3 Business Days |
Additional Information
| Alternative name | TNF-Alpha |
| Isotype | IgG |
| Clone | TN3-19-12 |
| Description | The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity.1 It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites.2 TNF-a is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-a secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-a has been detected in synovial fluid of patients with rheumatoid arthritis. |
| Specificity | Armenian Hamster Anti-Mouse TNFa (Clone TN3-19.12) recognizes Mouse TNFa. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Synonyms | DIF, TNFA, TNFSF2, TNF-alpha, B12, B61, EDP1, MGC2317, Edp1, Edp-1, Tnfip1, Tnfa, RATTNF, MGC124630, zgc:55302, wu:fi06b02, TNFAIP1, TNF, tnf, DKFZp468A2328, Tnfsf1a, TNFalpha, MGC151434, TNFa, cTNF, Tnf-alpha, tnfa-like, TNF-ALPHA, dif, tnfa, xtnf, TNF-a, tnfsf2, tnf-alpha, Cachectin |
Application Details
| Application Notes | FC, WB. Each Investigator should determine their own optimal working dilution for specific applications. |
| Concentration | 0.1 mg/ml |
| Purification | Purified |
| Buffer | This purified antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. Storage and Stability This antibody is stable for at least one week when stored at 2-8C. For long term sto |
| Storage | This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at 20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Restrictions | For Research Use only |
Publications
| Product |
Taylor, Wilkison, Voyich et al.: "Prevention of bone marrow cell apoptosis and regulation of hematopoiesis by type I IFNs during systemic responses to pneumocystis lung infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 5956-67, 2011 (PubMed).
Further details: Anti Ermann, Garrett, Kuchroo et al.: "Severity of innate immune-mediated colitis is controlled by the cytokine deficiency-induced colitis susceptibility-1 (Cdcs1) locus." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 17, pp. 7137-41, 2011 (PubMed). |
Alternatives
Alternatives for antigen "Tumor Necrosis Factor (TNF)", type "Antibodies"
