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Histone 3 antibody (H3K27me2, H3K27me3)

H3 Reactivity: Human WB, IF, ICC Host: Mouse Monoclonal 7B11 unconjugated
Catalog No. ABIN4889658
  • Target See all Histone 3 (H3) Antibodies
    Histone 3 (H3)
    Binding Specificity
    • 60
    • 47
    • 45
    • 42
    • 41
    • 37
    • 36
    • 35
    • 35
    • 34
    • 34
    • 32
    • 31
    • 30
    • 29
    • 29
    • 26
    • 25
    • 23
    • 23
    • 23
    • 22
    • 20
    • 18
    • 18
    • 17
    • 17
    • 16
    • 16
    • 16
    • 16
    • 16
    • 15
    • 14
    • 14
    • 13
    • 13
    • 12
    • 12
    • 12
    • 12
    • 12
    • 11
    • 11
    • 10
    • 10
    • 10
    • 9
    • 9
    • 8
    H3K27me2, H3K27me3
    Reactivity
    • 1402
    • 941
    • 861
    • 59
    • 42
    • 41
    • 41
    • 40
    • 39
    • 35
    • 35
    • 30
    • 29
    • 22
    • 19
    • 6
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 1220
    • 243
    • 8
    • 4
    Mouse
    Clonality
    • 1121
    • 353
    • 1
    Monoclonal
    Conjugate
    • 824
    • 81
    • 63
    • 63
    • 63
    • 62
    • 62
    • 62
    • 37
    • 33
    • 23
    • 17
    • 17
    • 17
    • 17
    • 17
    • 14
    • 2
    • 1
    This Histone 3 antibody is un-conjugated
    Application
    • 1061
    • 411
    • 381
    • 316
    • 254
    • 188
    • 181
    • 180
    • 163
    • 161
    • 141
    • 127
    • 119
    • 48
    • 38
    • 34
    • 32
    • 20
    • 16
    • 14
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Purification
    Protein A Chromatography
    Immunogen
    This Histone H3 di/trimethylLys27 antibody was raised against a peptide including trimethyllysine 27 of histone H3.
    Clone
    7B11
    Isotype
    IgG
    Top Product
    Discover our top product H3 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice

    Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

    Storage
    -20 °C
    Storage Comment
    Antibodies in solution can be stored at -20 °C for 2 years.
    Expiry Date
    6 months
  • Nolan, Franco, Hance, Hayward, Isaacs: "Tumor-secreted Hsp90 subverts polycomb function to drive prostate tumor growth and invasion." in: The Journal of biological chemistry, Vol. 290, Issue 13, pp. 8271-82, (2015) (PubMed).

    Papazyan, Voronina, Chapman, Luperchio, Gilbert, Meier, Mackintosh, Shabanowitz, Tackett, Reddy, Coyne, Hunt, Liu, Taverna: "Methylation of histone H3K23 blocks DNA damage in pericentric heterochromatin during meiosis." in: eLife, Vol. 3, pp. e02996, (2014) (PubMed).

    Ivanov, Pawlikowski, Manoharan, van Tuyn, Nelson, Rai, Shah, Hewitt, Korolchuk, Passos, Wu, Berger, Adams: "Lysosome-mediated processing of chromatin in senescence." in: The Journal of cell biology, Vol. 202, Issue 1, pp. 129-43, (2013) (PubMed).

    Rada-Iglesias, Bajpai, Prescott, Brugmann, Swigut, Wysocka: "Epigenomic annotation of enhancers predicts transcriptional regulators of human neural crest." in: Cell stem cell, Vol. 11, Issue 5, pp. 633-48, (2012) (PubMed).

  • Target
    Histone 3 (H3)
    Alternative Name
    Histone H3 (H3 Products)
    Synonyms
    H-3 antibody, histocompatibility 3 antibody, H3 antibody
    Molecular Weight
    17 kDa
    Gene ID
    3020
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