CLEC7A antibody (C-Type Lectin Domain Family 7, Member A) (AA 66-201) (PE)

Details for Product anti-CLEC7A Antibody No. ABIN4897736, Supplier: Log in to see
Antigen
  • CLEC7A
  • BGR
  • Clecsf12
  • beta-GR
  • CANDF4
  • CLECSF12
  • DECTIN1
  • Clec7b
  • RGD1565140
  • C-type lectin domain family 7, member A
  • C-type lectin domain family 7, member a
  • dendritic cell-associated C-type lectin 1
  • CLEC7A
  • Clec7a
  • LOC100339146
Alternatives
anti-Human CLEC7A antibody for Blocking Reagent
Epitope
AA 66-201
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Reactivity
Human
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2
Host
Mouse
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1
Clonality (Clone)
Monoclonal ()
Conjugate
This CLEC7A antibody is conjugated to PE
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Application
Flow Cytometry (FACS)
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59
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13
8
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3
1
1
Options
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Immunogen Mouse myeloma cell line NS0-derived recombinant human Dectin-1/CLEC7A, Thr66-Met201, Accession # NP_072092
Clone 259931
Isotype IgG2b
Specificity Detects human Dectin-1/CLEC7A in direct ELISAs. In directs ELISAs, less than 10 % cross-reactivity with recombinant human (rh) DLEC and no cross-reactivity with recombinant mouse Dectin-1 or rhDectin-2 is observed.
Characteristics Clone 259931 was used by HLDA to establish CD designation
Purification Protein A or G purified from hybridoma culture supernatant
Alternative Name Dectin-1/CLEC7A (CLEC7A Antibody Abstract)
Background Alternative Names: Beta-glucan receptor, BGR, CD369, CLEC7A, CLECSF12, CLECSF12DC-associated C-type lectin 1, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamilymember 12, C-type lectin domain family 7 member A, C-type lectin domain family 7, member A, C-type lectin superfamily member 12, dectin-1, Dectin1, DECTIN1CANDF4, Dendritic cell-associated C-type lectin 1, dendritic cell-associated C-type lectin-1, hDectin-1, lectin-like receptor 1
Gene ID 64581
NCBI Accession NP_072092
Pathways Activation of Innate immune Response
Application Notes Flow Cytometry 10 uL/10^6 cells
Restrictions For Research Use only
Format Liquid
Buffer Supplied in a saline solution containing BSA and Sodium Azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Protect from light. Do not freeze. 12 months from date of receipt,2°C to 8°C as supplied.
Expiry Date 12 months
Supplier Images
Flow Cytometry (FACS) image for anti-CLEC7A antibody (C-Type Lectin Domain Family 7, Member A) (AA 66-201) (PE) (ABIN4897736) Detection of Dectin-1/CLEC7A in Human Blood Monocytes by Flow Cytometry. Human periph...
Flow Cytometry (FACS) image for anti-CLEC7A antibody (C-Type Lectin Domain Family 7, Member A) (AA 66-201) (PE) (ABIN4897736) Detection of Dectin-1/CLEC7A in Human Blood Monocytes by Flow Cytometry. Human periph...
Product cited in: Cardone, Ikeda, Varano, Belardelli, Millefiorini, Gessani, Conti: "Opposite regulatory effects of IFN-β and IL-3 on C-type lectin receptors, antigen uptake, and phagocytosis in human macrophages." in: Journal of leukocyte biology, Vol. 95, Issue 1, pp. 161-8, 2014 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Punsmann, Liebers, Lotz, Brüning, Raulf: "Ex vivo cytokine release and pattern recognition receptor expression of subjects exposed to dampness: pilot study to assess the outcome of mould exposure to the innate immune system." in: PLoS ONE, Vol. 8, Issue 12, pp. e82734, 2013 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Li, Dong, Tong, Wang, Liu, Wang, Liu, Chen, Xu, Chen, Duan: "MBL-mediated opsonophagocytosis of Candida albicans by human neutrophils is coupled with intracellular Dectin-1-triggered ROS production." in: PLoS ONE, Vol. 7, Issue 12, pp. e50589, 2012 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Khoo, Chai, Koenen, Oosting, Steinmeyer, Zuegel, Joosten, Netea, van der Ven: "Vitamin D(3) down-regulates proinflammatory cytokine response to Mycobacterium tuberculosis through pattern recognition receptors while inducing protective cathelicidin production." in: Cytokine, Vol. 55, Issue 2, pp. 294-300, 2011 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Cunha, Di Ianni, Bozza, Giovannini, Zagarella, Zelante, DAngelo, Pierini, Pitzurra, Falzetti, Carotti, Perruccio, Latgé, Rodrigues, Velardi, Aversa, Romani, Carvalho et al.: "Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of ..." in: Blood, Vol. 116, Issue 24, pp. 5394-402, 2010 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Llinàs, Lázaro, de Salort, Matesanz-Isabel, Sintes, Engel: "Expression profiles of novel cell surface molecules on B-cell subsets and plasma cells as analyzed by flow cytometry." in: Immunology letters, Vol. 134, Issue 2, pp. 113-21, 2010 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).