CXCL10 antibody (Chemokine (C-X-C Motif) Ligand 10) (AA 22-98)

Details for Product anti-CXCL10 Antibody No. ABIN4899706, Supplier: Log in to see
Antigen
  • CXCL10
  • C7
  • IFI10
  • INP10
  • IP-10
  • SCYB10
  • crg-2
  • gIP-10
  • mob-1
  • CRG-2
  • IP10
  • Ifi10
  • Scyb10
  • chemokine (C-X-C motif) ligand 10
  • C-X-C motif chemokine 10
  • CXCL10
  • cxl10
  • Cxcl10
Epitope
AA 22-98
54
15
4
4
3
3
1
1
Reactivity
Human
231
69
46
11
7
5
4
4
4
2
2
Host
Mouse
197
111
15
9
5
2
Clonality (Clone)
Monoclonal ()
Conjugate
This CXCL10 antibody is un-conjugated
56
27
16
8
5
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
256
185
85
69
41
24
23
23
22
16
13
8
8
5
5
4
3
3
3
3
2
2
Options
Supplier
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Supplier Product No.
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Immunogen E. coli-derived recombinant human CXCL10/IP-10/CRG-2, Val22-Pro98, Accession # P02778.2
Clone 33036
Isotype IgG1
Specificity Detects human CXCL10/IP-10/CRG-2 in ELISAs and Western blots. In Western blots, does not cross-react with recombinant human CXCL1, 2, 3, 5, 8, 9, 12/SDF-1 beta , recombinant mouse CXCL1, or 2.
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Alternative Name CXCL10/IP-10/CRG-2 (CXCL10 Antibody Abstract)
Background Alternative Names: C7, chemokine (C-X-C motif) ligand 10, crg-2, CRG2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10
Gene ID 3627
UniProt P02778
Research Area Chemokines
Application Notes Western Blot 1 μg/mL
Neutralization 0.5-2.0 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
ELISA Capture (Matched Antibody Pair) 2-8 μg/mL
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Neutralization (Neut) image for anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) antibody (ABIN4899706) Chemotaxis Induced by CXCL10/IP-10 and Neutralization by Human CXCL10/IP-10 Antibody....
Neutralization (Neut) image for anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) antibody (ABIN4899706) Chemotaxis Induced by CXCL10/IP-10 and Neutralization by Human CXCL10/IP-10 Antibody....
Product cited in: Connelly, Kandane-Rathnayake, Hoi, Nikpour, Morand: "Association of MIF, but not type I interferon-induced chemokines, with increased disease activity in Asian patients with systemic lupus erythematosus." in: Scientific reports, Vol. 6, pp. 29909, 2016 (PubMed). (Sample species: Human).

Schutte, Fisher, Burdick, Mehrad, Mathers, Mann, Nakamoto, Hughes: "Escherichia coli Pyruvate Dehydrogenase Complex Is an Important Component of CXCL10-Mediated Antimicrobial Activity." in: Infection and immunity, Vol. 84, Issue 1, pp. 320-8, 2015 (PubMed). Method employed by authors: Immunoassay (IA) (Sample species: Human).

Srivastava, Lee, Andrade Filho, Lord, Jie, Davidson, López-Albaitero, Gibson, Gooding, Ferrone, Ferris: "Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 19, Issue 7, pp. 1858-72, 2013 (PubMed). Method employed by authors: Functional Studies (Func) (Sample species: Human).

Nakajima, Van Tin, Sato, Thach, Katano, Diep, Kumasaka, Thuy, Hasegawa, San, Kawachi, Liem, Suzuki, Sata: "Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 3, pp. 357-69, 2013 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Xu, Joo, Clayton, Dullaers, Herve, Blankenship, De La Morena, Balderas, Picard, Casanova, Pascual, Oh, Banchereau: "Macrophages induce differentiation of plasma cells through CXCL10/IP-10." in: The Journal of experimental medicine, Vol. 209, Issue 10, pp. 1813-23, S1-2, 2012 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Zahn, Rehkämper, Kümmerer, Ferring-Schmidt, Bieber, Tüting, Wenzel: "Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFNλ) in cutaneous lupus erythematosus." in: The Journal of investigative dermatology, Vol. 131, Issue 1, pp. 133-40, 2010 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Yoon, Park, You, Choi, Lee, Im, Park, Pflugfelder: "Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome." in: Investigative ophthalmology & visual science, Vol. 51, Issue 2, pp. 643-50, 2010 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Oo, Weston, Lalor, Curbishley, Withers, Reynolds, Shetty, Harki, Shaw, Eksteen, Hubscher, Walker, Adams: "Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 6, pp. 2886-98, 2010 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Franciszkiewicz, Le Floch, Jalil, Vigant, Robert, Vergnon, Mackiewicz, Benihoud, Validire, Chouaib, Combadière, Mami-Chouaib: "Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention." in: Cancer research, Vol. 69, Issue 15, pp. 6249-55, 2009 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Biancotto, Iglehart, Lisco, Vanpouille, Grivel, Lurain, Reichelderfer, Margolis: "Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo." in: AIDS research and human retroviruses, Vol. 24, Issue 3, pp. 453-62, 2008 (PubMed). Method employed by authors: Luminex Assay (LMNX) (Sample species: Human).

Qui, Ferrell, Nolan, Phelps, Tabibiazar, Whitney, Naelfski: "Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines." in: Clinical chemistry, Vol. 53, Issue 11, pp. 2010-2, 2007 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Human).

Cheadle, Riyad, Subar, Rothwell, Ashton, Batha, Sherlock, Hawkins, Gilham: "Eotaxin-2 and colorectal cancer: a potential target for immune therapy." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 13, Issue 19, pp. 5719-28, 2007 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Human).

Liu, Bates, Jarjour, Busse, Bertics, Kelly: "Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 7, pp. 4840-8, 2007 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Human).

Winter, Moser, Kriehuber, Wiesner, Knobler, Trautinger, Bombosi, Stingl, Petzelbauer, Rot, Maurer: "Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 4272-82, 2007 (PubMed). Method employed by authors: Immunodepletion (IDe) (Sample species: Human).

Pfleger, Schloot, ter Veld: "Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays." in: Journal of immunological methods, Vol. 329, Issue 1-2, pp. 214-8, 2007 (PubMed). Method employed by authors: Luminex Assay (LMNX) (Sample species: Human).

Biancotto, Grivel, Iglehart, Vanpouille, Lisco, Sieg, Debernardo, Garate, Rodriguez, Margolis, Lederman: "Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1." in: Blood, Vol. 109, Issue 10, pp. 4272-9, 2007 (PubMed). Method employed by authors: Luminex Assay (LMNX) (Sample species: Human).

Grivel, Elliott, Lisco, Biancotto, Condack, Shattock, McGowan, Margolis, Anton: "HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1." in: AIDS, Vol. 21, Issue 10, pp. 1263-72, 2007 (PubMed). Method employed by authors: Luminex Assay (LMNX) (Sample species: Human).

Edwards, Johnson, Johnston: "Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells." in: American journal of respiratory cell and molecular biology, Vol. 34, Issue 5, pp. 616-24, 2006 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Human).

Gounni Abdelilah, Wellemans, Agouli, Guenounou, Hamid, Beck, Lamkhioued: "Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines." in: Clinical immunology (Orlando, Fla.), Vol. 120, Issue 2, pp. 220-31, 2006 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Wenzel, Wörenkämper, Freutel, Henze, Haller, Bieber, Tüting: "Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus." in: The Journal of pathology, Vol. 205, Issue 4, pp. 435-42, 2005 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

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