CXCL10 antibody (Chemokine (C-X-C Motif) Ligand 10) (AA 22-98)

Details for Product anti-CXCL10 Antibody No. ABIN4899708, Supplier: Log in to see
Antigen
  • CXCL10
  • C7
  • IFI10
  • INP10
  • IP-10
  • SCYB10
  • crg-2
  • gIP-10
  • mob-1
  • CRG-2
  • IP10
  • Ifi10
  • Scyb10
  • chemokine (C-X-C motif) ligand 10
  • C-X-C motif chemokine 10
  • CXCL10
  • cxl10
  • Cxcl10
Epitope
AA 22-98
54
15
4
4
3
3
1
1
Reactivity
Human
231
69
46
11
7
5
4
4
4
2
2
Host
Goat
197
112
15
8
5
2
Clonality
Polyclonal
Conjugate
This CXCL10 antibody is un-conjugated
56
27
16
8
5
5
4
4
4
4
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut), Western Blotting (WB)
256
185
85
69
41
24
23
22
22
16
13
8
8
5
5
4
4
3
3
3
2
2
Options
Supplier
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Supplier Product No.
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Immunogen E. coli-derived recombinant human CXCL10/IP-10/CRG-2, Val22-Pro98, Accession # P02778
Isotype IgG
Specificity Detects human CXCL10/IP-10/CRG-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 10 % cross-reactivity with recombinant mouse CRG-2, recombinant human (rh) MIG, and rhGRO gamma .
Purification Antigen Affinity-purified
Sterility 0.2 μm filtered
Endotoxin Level <0.20 EU per 1 μg of the antibody by the LAL method.
Alternative Name CXCL10/IP-10/CRG-2 (CXCL10 Antibody Abstract)
Background Alternative Names: C7, chemokine (C-X-C motif) ligand 10, crg-2, CRG2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10
Gene ID 3627
UniProt P02778
Research Area Chemokines
Application Notes Western Blot 0.1 μg/mL
Neutralization 1-4 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 5-15 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.2 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Neutralization (Neut) image for anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) antibody (ABIN4899708) Chemotaxis Induced by CXCL10/IP-10 and Neutralization by Human CXCL10/IP-10 Antibody....
Immunocytochemistry (ICC) image for anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) antibody (ABIN4899708) CXCL10/IP-10 in Human PBMCs. CXCL10/IP-10 was detected in immersion fixed PHA-treated...
Neutralization (Neut) image for anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) antibody (ABIN4899708) Chemotaxis Induced by CXCL10/IP-10 and Neutralization by Human CXCL10/IP-10 Antibody....
Immunocytochemistry (ICC) image for anti-Chemokine (C-X-C Motif) Ligand 10 (CXCL10) (AA 22-98) antibody (ABIN4899708) CXCL10/IP-10 in Human PBMCs. CXCL10/IP-10 was detected in immersion fixed PHA-treated...
Product cited in: Dai, Xing, Cerise, Wang, Jabbari, de Jong, Petukhova, Christiano, Clynes: "CXCR3 Blockade Inhibits T Cell Migration into the Skin and Prevents Development of Alopecia Areata." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 4, pp. 1089-99, 2016 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Liu, Zeng, Wang, Fu, Wang, Liu, Ren, Yu, Zheng, Hu, Shi, Xu: "Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 63, 2016 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Sarkar, Lee, Victorino, Nguyen, Walters, Burrack, Eberlein, Hildemann, Homann: "Expression and regulation of chemokines in murine and human type 1 diabetes." in: Diabetes, Vol. 61, Issue 2, pp. 436-46, 2012 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Shan, Cheng, Song, Roberts, Green, Hacken-Bitar, Huh, Bakaeen, Coxson, Storness-Bliss, Ramchandani, Lee, Corry, Kheradmand: "Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema." in: Science translational medicine, Vol. 1, Issue 4, pp. 4ra10, 2010 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Maingat, Viappiani, Zhu, Vivithanaporn, Ellestad, Holden, Silva, Power: "Regulation of lentivirus neurovirulence by lipopolysaccharide conditioning: suppression of CXCL10 in the brain by IL-10." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 184, Issue 3, pp. 1566-74, 2010 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Cat (Feline)).

Okumura, Yuki, Kobayashi, Okamura, Ohmori, Saito, Ra, Okayama: "Hyperexpression of NOD2 in intestinal mast cells of Crohn's disease patients: preferential expression of inflammatory cell-recruiting molecules via NOD2 in mast cells." in: Clinical immunology (Orlando, Fla.), Vol. 130, Issue 2, pp. 175-85, 2009 (PubMed). Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Human).

Kim, Romero, Kim, Tarca, Chhauy, LaJeunesse, Lee, Draghici, Gotsch, Kusanovic, Hassan, Kim et al.: "Villitis of unknown etiology is associated with a distinct pattern of chemokine up-regulation in the feto-maternal and placental compartments: implications for conjoint maternal allograft rejection ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 6, pp. 3919-27, 2009 (PubMed). Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Human).

van Heteren, Rozenberg, Aronica, Troost, Lebon, Kuijpers: "Astrocytes produce interferon-alpha and CXCL10, but not IL-6 or CXCL8, in Aicardi-Goutières syndrome." in: Glia, Vol. 56, Issue 5, pp. 568-78, 2008 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Datta, Flaxenburg, Laxmanan, Geehan, Grimm, Waaga-Gasser, Briscoe, Pal: "Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer." in: Cancer research, Vol. 66, Issue 19, pp. 9509-18, 2006 (PubMed). Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Human).

Meller, Winterberg, Gilliet, Müller, Lauceviciute, Rieker, Neumann, Kubitza, Gombert, Bünemann, Wiesner, Franken-Kunkel, Kanzler, Dieu-Nosjean, Amara, Ruzicka, Lehmann, Zlotnik, Homey: "Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus." in: Arthritis and rheumatism, Vol. 52, Issue 5, pp. 1504-16, 2005 (PubMed). Method employed by authors: Immunohistochemistry (Frozen Sections) (IHC (fro)) (Sample species: Human).

van Marle, Henry, Todoruk, Sullivan, Silva, Rourke, Holden, McArthur, Gill, Power: "Human immunodeficiency virus type 1 Nef protein mediates neural cell death: a neurotoxic role for IP-10." in: Virology, Vol. 329, Issue 2, pp. 302-18, 2004 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Ohshima, Karube, Kawano, Tsuchiya, Suefuji, Yamaguchi, Suzumiya, Kikuchii: "Classification of distinct subtypes of peripheral T-cell lymphoma unspecified, identified by chemokine and chemokine receptor expression: Analysis of prognosis." in: International journal of oncology, Vol. 25, Issue 3, pp. 605-13, 2004 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Giunti, Borsellino, Benelli, Marchese, Capello, Valle, Pedemonte, Noonan, Albini, Bernardi, Mancardi, Battistini, Uccelli: "Phenotypic and functional analysis of T cells homing into the CSF of subjects with inflammatory diseases of the CNS." in: Journal of leukocyte biology, Vol. 73, Issue 5, pp. 584-90, 2003 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Keane, Donnelly, Belperio, Goodman, Dy, Burdick, Fishbein, Strieter: "Imbalance in the expression of CXC chemokines correlates with bronchoalveolar lavage fluid angiogenic activity and procollagen levels in acute respiratory distress syndrome." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 169, Issue 11, pp. 6515-21, 2002 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Human).

Lauw, Dekkers, te Velde, Speelman, Levi, Kurimoto, Hack, van Deventer, van der Poll: "Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees." in: The Journal of infectious diseases, Vol. 179, Issue 3, pp. 646-52, 1999 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Chimpanzee).

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