Interleukin 8 antibody (IL8) (AA 28-99)

Details for Product anti-IL8 Antibody No. ABIN4900106, Supplier: Log in to see
Antigen
  • IL8
  • K60
  • interleukin-8
  • il8
  • si:dkey-151b16.2
  • cxcli2
  • Il8
  • Scyb15
  • lungkine
  • weche
  • CXCL8
  • GCP-1
  • GCP1
  • LECT
  • LUCT
  • LYNAP
  • MDNCF
  • MONAP
  • NAF
  • NAP-1
  • NAP1
  • IL-8
  • AMCF-I
  • EMF-1
  • interleukin 8-like 1
  • interleukin 8
  • chemokine (C-X-C motif) ligand 1-like
  • chemokine (C-X-C motif) ligand 15
  • interleukin 8-like 2
  • interleukin-8-like
  • IL8L1
  • il8
  • IL8
  • LOC422654
  • Cxcl15
  • Il8
  • IL8L2
  • IL*08-02
Alternatives
anti-Human Interleukin 8 antibody for ELISA
Epitope
AA 28-99
52
31
23
14
13
11
8
7
6
5
4
2
2
2
2
1
1
1
1
1
1
Reactivity
Human
420
31
24
19
18
15
14
9
8
7
6
5
4
4
4
1
1
1
1
1
Host
Mouse
309
221
9
6
6
5
2
Clonality (Clone)
Monoclonal ()
Conjugate
This Interleukin 8 antibody is un-conjugated
60
47
16
10
6
4
4
4
4
4
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
Application
Cytometry by Time of Flight (CyTOF), ELISA (Capture), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut), Western Blotting (WB)
373
355
127
96
37
35
35
32
26
23
23
15
13
12
10
5
4
3
2
2
2
2
2
2
2
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen E. coli-derived recombinant human IL-8/CXCL8, Ser28-Ser99, Accession # P10145
Clone 6217
Isotype IgG1
Specificity Detects human IL-8/CXCL8 in ELISAs and Western blots. In Western blots, 100 % cross-reactivity with recombinant porcine IL-8/CXCL8 and no cross-reactivity with recombinant rat CXCL3/CINC-2 alpha is observed.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Alternative Name CXCL8/IL-8 (IL8 Antibody Abstract)
Background Alternative Names: 3-10C, AMCF-I, C-X-C motif chemokine 8, CXCL8, CXCL8SCYB8, Emoctakin, GCP1, GCP-1TSG-1, IL8, interleukin 8, K60, LAI, LECT, MDNCF, MDNCFb-ENAP, member 8, MONAPGCP1, NAP1, NAP-1NAP1, NCF, Neutrophil-activating protein 1, Protein 3-10C, T cell chemotactic factor, T-cell chemotactic factor, TCF, TSG1
Gene ID 3576
UniProt P10145
Research Area Angiogenesis, Cytokines, Innate Immunity, Cancer
Pathways Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
Application Notes Western Blot 1 μg/mL
Neutralization 0.08-0.4 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
ELISA Capture (Matched Antibody Pair) 2-8 μg/mL
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Neutralization (Neut) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900106) Chemotaxis Induced by CXCL8/IL-8 and Neutralization by Human CXCL8/IL-8 Antibody. Rec...
Immunocytochemistry (ICC) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900106) CXCL8/IL-8 in Human PBMCs. CXCL8/IL-8 was detected in immersion fixed human periphera...
Neutralization (Neut) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900106) Chemotaxis Induced by IL-8/CXCL8 and Neutralization by Human IL-8/CXCL8 Antibody. Rec...
Immunocytochemistry (ICC) image for anti-Interleukin 8 (IL8) (AA 28-99) antibody (ABIN4900106) IL-8/CXCL8 in Human PBMCs. IL-8/CXCL8 was detected in immersion fixed human periphera...
Product cited in: Delitto, Delitto, DiVita, Pham, Han, Hartlage, Newby, Gerber, Behrns, Moldawer, Thomas, George, Brusko, Mathews, Liu, Trevino, Hughes, Wallet: "Human Pancreatic Cancer Cells Induce a MyD88-Dependent Stromal Response to Promote a Tumor-Tolerant Immune Microenvironment." in: Cancer research, Vol. 77, Issue 3, pp. 672-683, 2016 (PubMed). Method employed by authors: Biochemical Assay (BCA) (Sample species: Human).

Han, Li, Xu, Islam, Khang, Del Sorbo, Lee, Szaszi, Zhong, Slutsky, Li, Zhang: "Tsr Chemoreceptor Interacts With IL-8 Provoking E. coli Transmigration Across Human Lung Epithelial Cells." in: Scientific reports, Vol. 6, pp. 31087, 2016 (PubMed). Method employed by authors: Immunoprecipitation (IP) (Sample species: Escherichia coli (E. coli)).

Jing, Xu, Chen, Zhong, Huang, Zhang, Guo, Yang, Ding, Chen, Huang: "The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer." in: PLoS ONE, Vol. 11, Issue 4, pp. e0152789, 2016 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Chao, Sun, Peng, Wu: "Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells." in: International journal of molecular sciences, Vol. 17, Issue 8, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Voltolini, Battersby, Novembri, Torricelli, Severi, Petraglia, Norman: "Urocortin 2 role in placental and myometrial inflammatory mechanisms at parturition." in: Endocrinology, Vol. 156, Issue 2, pp. 670-9, 2015 (PubMed). Method employed by authors: ELISA (Capture) (ELISA (Capture)) (Sample species: Human).

Takeuchi, Baghdadi, Tsuchikawa, Wada, Nakamura, Abe, Nakanishi, Usui, Higuchi, Takahashi, Inoko, Sato, Takano, Shichinohe, Seino, Hirano: "Chemotherapy-Derived Inflammatory Responses Accelerate the Formation of Immunosuppressive Myeloid Cells in the Tissue Microenvironment of Human Pancreatic Cancer." in: Cancer research, Vol. 75, Issue 13, pp. 2629-40, 2015 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Gouwy, De Buck, Pörtner, Opdenakker, Proost, Struyf, Van Damme: "Serum amyloid A chemoattracts immature dendritic cells and indirectly provokes monocyte chemotaxis by induction of cooperating CC and CXC chemokines." in: European journal of immunology, Vol. 45, Issue 1, pp. 101-12, 2015 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Chen, Min, Wang, Zhao, Chen, Qin, Chen, Shen, Tang, Gan, Ruan, Sun, Qin, Gu: "Loss of RACK1 Promotes Metastasis of Gastric Cancer by Inducing a miR-302c/IL8 Signaling Loop." in: Cancer research, Vol. 75, Issue 18, pp. 3832-41, 2015 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

McElvaney, OReilly, White, Lacey, Pohl, Gerlza, Bergin, Kerr, McCarthy, OBrien, Adage, Kungl, Reeves, McElvaney: "The effect of the decoy molecule PA401 on CXCL8 levels in bronchoalveolar lavage fluid of patients with cystic fibrosis." in: Molecular immunology, Vol. 63, Issue 2, pp. 550-8, 2014 (PubMed). Method employed by authors: Biochemical Assay (BCA) (Sample species: Human).

Khanna, Chung, Neves, Robertson, Dong: "CD82/KAI expression prevents IL-8-mediated endothelial gap formation in late-stage melanomas." in: Oncogene, Vol. 33, Issue 22, pp. 2898-908, 2014 (PubMed). Method employed by authors: ELISA (Capture) (ELISA (Capture)) (Sample species: Human).

Kuravi, McGettrick, Satchell, Saleem, Harper, Williams, Rainger, Savage: "Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 1, pp. 234-43, 2014 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Nakajima, Van Tin, Sato, Thach, Katano, Diep, Kumasaka, Thuy, Hasegawa, San, Kawachi, Liem, Suzuki, Sata: "Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 3, pp. 357-69, 2013 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Sahlander, Larsson, Palmberg: "Daily exposure to dust alters innate immunity." in: PLoS ONE, Vol. 7, Issue 2, pp. e31646, 2012 (PubMed). Method employed by authors: ELISA (ELISA) (Sample species: Human).

Gelderblom, Weymar, Bernreuther, Velden, Arunachalam, Steinbach, Orthey, Arumugam, Leypoldt, Simova, Thom, Friese, Prinz, Hölscher, Glatzel, Korn, Gerloff, Tolosa, Magnus: "Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke." in: Blood, Vol. 120, Issue 18, pp. 3793-802, 2012 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Bellini, Marini, Bianchetti, Barczyk, Schmidt, Mattoli: "Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients." in: Mucosal immunology, Vol. 5, Issue 2, pp. 140-9, 2012 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Meda, Molla, De Pizzol, Regano, Maione, Capano, Locati, Mantovani, Latini, Bussolino, Giraudo: "Semaphorin 4A exerts a proangiogenic effect by enhancing vascular endothelial growth factor-A expression in macrophages." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 8, pp. 4081-92, 2012 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Nicolaidou, Wong, Redpath, Ersek, Baban, Williams, Cope, Horwood: "Monocytes induce STAT3 activation in human mesenchymal stem cells to promote osteoblast formation." in: PLoS ONE, Vol. 7, Issue 7, pp. e39871, 2012 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Xu, Joo, Clayton, Dullaers, Herve, Blankenship, De La Morena, Balderas, Picard, Casanova, Pascual, Oh, Banchereau: "Macrophages induce differentiation of plasma cells through CXCL10/IP-10." in: The Journal of experimental medicine, Vol. 209, Issue 10, pp. 1813-23, S1-2, 2012 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Zepp, Nold-Petry, Dinarello, Nold: "Protection from RNA and DNA viruses by IL-32." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 7, pp. 4110-8, 2011 (PubMed). (Sample species: Human).

Chang, Al-Alwan, Risse, Roussel, Rousseau, Halayko, Martin, Hamid, Eidelman: "TH17 cytokines induce human airway smooth muscle cell migration." in: The Journal of allergy and clinical immunology, Vol. 127, Issue 4, pp. 1046-53.e1-2, 2011 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

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