Interleukin 6 antibody (IL6) (AA 30-212)

Details for Product anti-IL6 Antibody No. ABIN4900155, Supplier: Log in to see
Antigen
  • Il-6
  • ILg6
  • Ifnb2
  • BSF2
  • HGF
  • HSF
  • IFNB2
  • IL-6
  • CHIL-6
  • il6
  • interleukin 6
  • interleukin 6 (interferon, beta 2)
  • interleukin-6
  • Il6
  • IL6
  • il-6
Alternatives
anti-Human Interleukin 6 antibody for Immunoprecipitation
Epitope
AA 30-212
66
49
27
20
15
15
15
14
13
10
10
10
9
8
7
7
6
6
5
3
3
3
2
1
1
1
1
1
1
Reactivity
Human
577
240
113
37
29
26
21
10
7
7
7
6
4
3
3
2
1
Host
Mouse
383
297
202
38
7
7
5
Clonality (Clone)
Monoclonal ()
Conjugate
This Interleukin 6 antibody is un-conjugated
106
40
26
23
15
13
13
11
11
9
9
9
7
7
6
5
5
5
5
5
4
4
4
3
3
3
3
3
3
2
2
2
2
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Neutralization (Neut)
591
538
223
153
124
97
70
66
58
48
41
38
19
17
15
13
12
8
7
5
4
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Immunogen E. coli-derived recombinant human IL-6, Val30-Met212, Accession # P05231
Clone 1936
Isotype IgG2b
Specificity Detects human IL-6 in direct ELISAs. Does not cross-react with recombinant IL-6 from mouse, rat, or pig.
Purification Protein A or G purified from hybridoma culture supernatant
Sterility 0.2 μm filtered
Endotoxin Level <0.20 EU per 1 μg of the antibody by the LAL method.
Alternative Name IL-6 (IL6 Antibody Abstract)
Background Alternative Names: B cell stimulatory factor-2, B-cell differentiation factor, BSF-2, BSF2CTL differentiation factor, CDF, HGFHSFIFNB2Hybridoma growth factor, IFN-beta-2, IL6, IL-6B-cell stimulatory factor 2, Interferon beta-2, interleukin 6 (interferon, beta 2), interleukin BSF-2, interleukin-6, MGI-2A
Gene ID 3569
UniProt P05231
Research Area Angiogenesis, Cytokines, Innate Immunity, Cancer
Pathways Hormone Transport, Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Carbohydrate Metabolic Process, Autophagy, Cell RedoxHomeostasis
Application Notes Neutralization 0.05-0.15 μg/mL
Intracellular Staining by Flow Cytometry 0.25 μg/10^6 cells
Immunocytochemistry 8-25 μg/mL
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS and NaCl with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Neutralization (Neut) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Cell Proliferation Induced by IL-6 and Neutralization by Human IL-6 Antibody. Recombi...
Flow Cytometry (FACS) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Detection of IL-6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclea...
Immunocytochemistry (ICC) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) IL-6 in Human PBMCs. IL-6 was detected in immersion fixed human peripheral blood mono...
Neutralization (Neut) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Cell Proliferation Induced by IL-6 and Neutralization by Human IL-6 Antibody. Recombi...
Flow Cytometry (FACS) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) Detection of IL-6 in Human PBMCs by Flow Cytometry. Human peripheral blood mononuclea...
Immunocytochemistry (ICC) image for anti-Interleukin 6 (IL6) (AA 30-212) antibody (ABIN4900155) IL-6 in Human PBMCs. IL-6 was detected in immersion fixed human peripheral blood mono...
Product cited in: Cheng, van Asten, Burns, Evans, Walter, Hashim, Hughes, Taams: "Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses." in: European journal of immunology, Vol. 46, Issue 9, pp. 2211-21, 2016 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Nakajima, Van Tin, Sato, Thach, Katano, Diep, Kumasaka, Thuy, Hasegawa, San, Kawachi, Liem, Suzuki, Sata: "Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 26, Issue 3, pp. 357-69, 2013 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Human).

Corvaisier, Delneste, Jeanvoine, Preisser, Blanchard, Garo, Hoppe, Barré, Audran, Bouvard, Saint-André, Jeannin: "IL-26 is overexpressed in rheumatoid arthritis and induces proinflammatory cytokine production and Th17 cell generation." in: PLoS biology, Vol. 10, Issue 9, pp. e1001395, 2012 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Steinbicker, Sachidanandan, Vonner, Yusuf, Deng, Lai, Rauwerdink, Winn, Saez, Cook, Szekely, Roy, Seehra, Cuny, Scadden, Peterson, Bloch, Yu: "Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation." in: Blood, Vol. 117, Issue 18, pp. 4915-23, 2011 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Maneechotesuwan, Wamanuttajinda, Kasetsinsombat, Huabprasert, Yaikwawong, Barnes, Wongkajornsilp: "Der p 1 suppresses indoleamine 2, 3-dioxygenase in dendritic cells from house dust mite-sensitive patients with asthma." in: The Journal of allergy and clinical immunology, Vol. 123, Issue 1, pp. 239-48, 2009 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Rodier, Coppé, Patil, Hoeijmakers, Muñoz, Raza, Freund, Campeau, Davalos, Campisi: "Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion." in: Nature cell biology, Vol. 11, Issue 8, pp. 973-9, 2009 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Chong, Boehlke, Zheng, Zhang, Han, Zacks: "Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment." in: Investigative ophthalmology & visual science, Vol. 49, Issue 7, pp. 3193-200, 2008 (PubMed). Method employed by authors: In vivo Studies (in vivo) (Sample species: Mouse (Murine)).

Ren, Lin, Li, Chen, Huang, Lui, Nicholls, Lan, Tam: "Up-regulation of macrophage migration inhibitory factor in infants with acute neonatal necrotizing enterocolitis." in: Histopathology, Vol. 46, Issue 6, pp. 659-67, 2005 (PubMed). Method employed by authors: Immunocytochemistry (ICC) (Sample species: Human).

Did you look for something else?