IL15 antibody (Interleukin 15) (AA 49-162)

Details for Product anti-IL15 Antibody No. ABIN4900389, Supplier: Log in to see
Antigen
  • IL15
  • AI503618
  • IL-15
  • interleukin 15
  • IL15
  • Il15
Alternatives
anti-Rat (Rattus) IL15 antibody for Western Blotting
Epitope
AA 49-162
74
12
11
7
6
5
5
5
5
4
1
1
1
1
1
1
1
Reactivity
Human
226
67
26
10
8
6
5
2
2
1
1
1
Host
Mouse
147
122
17
17
5
5
Clonality (Clone)
Monoclonal ()
Conjugate
This IL15 antibody is un-conjugated
36
17
11
9
7
5
5
5
5
5
4
3
3
3
3
3
3
3
2
2
2
2
1
1
Application
Cytometry by Time of Flight (CyTOF), Flow Cytometry (FACS), Neutralization (Neut), Western Blotting (WB)
205
182
66
33
31
29
24
16
13
11
10
7
5
4
3
3
2
1
1
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen E. coli-derived recombinant human IL-15, Asn49-Ser162, Accession # P40933
Clone 34559
Isotype IgG1
Specificity Detects human IL-15 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2, recombinant mouse IL-15, or rhIL-21 is observed.
Purification Protein A or G purified from ascites
Sterility 0.2 μm filtered
Endotoxin Level <0.10 EU per 1 μg of the antibody by the LAL method.
Alternative Name IL-15 (IL15 Antibody Abstract)
Background Alternative Names: IL15, IL-15MGC9721, interleukin 15, interleukin-15
Gene ID 3600
UniProt P40933
Research Area Immunology, Cytokines, Innate Immunity
Pathways JAK-STAT Signaling, Glycosaminoglycan Metabolic Process
Application Notes Western Blot 1 μg/mL
Neutralization 0.1-0.5 μg/mL
Intracellular Staining by Flow Cytometry 2.5 μg/10^6 cells
CyTOF-ready
Restrictions For Research Use only
Reconstitution Reconstitute at 0.5 mg/mL in sterile PBS.
Buffer Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Preservative Without preservative
Storage 4 °C,-20 °C,-80 °C
Storage Comment Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt,-20°C to -70°C as supplied. 1 month,2°C to 8°C under sterile conditions after reconstitution. 6 months,-20°C to -70°C under sterile conditions after reconstitution.
Expiry Date 12 months
Supplier Images
Neutralization (Neut) image for anti-Interleukin 15 (IL15) (AA 49-162) antibody (ABIN4900389) Cell Proliferation Induced by IL-15 and Neutralization by Human IL-15 Antibody. Recom...
Neutralization (Neut) image for anti-Interleukin 15 (IL15) (AA 49-162) antibody (ABIN4900389) Cell Proliferation Induced by IL-15 and Neutralization by Human IL-15 Antibody. Recom...
Product cited in: Ciccocioppo, Gallia, Avanzini, Betti, Picone, Vanoli, Paganini, Biagi, Maccario, Corazza: "A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions." in: Mayo Clinic proceedings, Vol. 91, Issue 6, pp. 812-9, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Anguille, Van Acker, Van den Bergh, Willemen, Goossens, Van Tendeloo, Smits, Berneman, Lion: "Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner." in: PLoS ONE, Vol. 10, Issue 5, pp. e0123340, 2015 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Marra, Mathew, Grigoriadis, Wu, Kyle-Cezar, Watkins, Rashid, De Rinaldis, Hessey, Gazinska, Hayday, Tutt: "IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers." in: Cancer research, Vol. 74, Issue 17, pp. 4908-21, 2014 (PubMed). Method employed by authors: Blocking Peptide (BP) (Sample species: Human).

Muntasell, Magri, Pende, Angulo, López-Botet: "Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection." in: Blood, Vol. 115, Issue 25, pp. 5170-9, 2010 (PubMed). Method employed by authors: Neutralization (Neut) (Sample species: Human).

Tsukamoto, Huang, Dorsey, Carns, Sharma: "Juxtacrine function of interleukin-15/interleukin-15 receptor system in tumour derived human B-cell lines." in: Clinical and experimental immunology, Vol. 146, Issue 3, pp. 559-66, 2006 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

Ong, Hamid, Travers, Strickland, Al Kerithy, Boguniewicz, Leung: "Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 1, pp. 505-10, 2001 (PubMed). Method employed by authors: Flow Cytometry (FACS) (Sample species: Human).

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