FKBP1B antibody
-
- Target See all FKBP1B Antibodies
- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
-
Reactivity
- Human, Mouse
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This FKBP1B antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Affinity purification
- Immunogen
- A synthetic Peptide of human FKBP1B
- Isotype
- IgG
- Top Product
- Discover our top product FKBP1B Primary Antibody
-
-
- Application Notes
-
WB 1:500 - 1:1000
IHC 1:20 - 1:50
IF 1:20 - 1:50 - Comment
-
Detected in heart muscle (at protein level), Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20C. Avoid freeze / thaw cycles.
-
- Target
- FKBP1B (FK506 Binding Protein 1B, 12.6 KDa (FKBP1B))
- Alternative Name
- FKBP1B (FKBP1B Products)
- Synonyms
- FKBP12.6 antibody, MGC68829 antibody, FKBP1B antibody, DKFZp459K1429 antibody, 12.6kDa antibody, AW494148 antibody, calstabin2 antibody, FKBP1L antibody, OTK4 antibody, PKBP1L antibody, PPIase antibody, FK506 binding protein 1B antibody, FK506 binding protein 1B L homeolog antibody, FK506 binding protein 1b antibody, FKBP1B antibody, fkbp1b.L antibody, fkbp1b antibody, Fkbp1b antibody
- Background
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms.
- Molecular Weight
- 11.783 kDa
- Gene ID
- 2281
- UniProt
- P68106
- Pathways
- Hormone Transport, Negative Regulation of Hormone Secretion, Negative Regulation of Transporter Activity
-