MAPK8IP1 antibody (Mitogen-Activated Protein Kinase 8 Interacting Protein 1)

Details for Product anti-MAPK8IP1 Antibody No. ABIN4904305, Supplier: Log in to see
Antigen
  • IB1
  • JIP-1
  • Jip1
  • Prkm8ip
  • Skip
  • mjip-2a
  • JIP1
  • Jip-1
  • Mapk8ip
  • PRKM8IP
  • mitogen-activated protein kinase 8 interacting protein 1
  • MAPK8IP1
  • LOC100344706
  • Mapk8ip1
Reactivity
Human, Mouse (Murine)
66
47
40
Host
Rabbit
71
2
1
Clonality
Polyclonal
Conjugate
This MAPK8IP1 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
58
31
17
13
9
7
4
3
2
2
1
Options
Supplier
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Immunogen Recombinant protein of human MAPK8IP1.
Isotype IgG
Characteristics This gene encodes a regulator of the pancreatic beta-cell function. It is highly similar to JIP-1, a mouse protein known to be a regulator of c-Jun amino-terminal kinase (Mapk8). This protein has been shown to prevent MAPK8 mediated activation of transcription factors, and to decrease IL-1 beta and MAP kinase kinase 1 (MEKK1) induced apoptosis in pancreatic beta cells. This protein also functions as a DNA-binding transactivator of the glucose transporter GLUT2. RE1-silencing transcription factor (REST) is reported to repress the expression of this gene in insulin-secreting beta cells. This gene is found to be mutated in a type 2 diabetes family, and thus is thought to be a susceptibility gene for type 2 diabetes.
Purification Affinity purification
Alternative Name MAPK8IP1 (MAPK8IP1 Antibody Abstract)
Gene ID 9479
UniProt Q9UQF2
Application Notes WB 1:200-1:2000
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freeze/thaw cycles.
Storage -20 °C
Storage Comment Store at -20°C.
Supplier Images
Western Blotting (WB) image for anti-Mitogen-Activated Protein Kinase 8 Interacting Protein 1 (MAPK8IP1) antibody (ABIN4904305) Western blot analysis of extract of various cells, using MAPK8IP1 antibody.
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