PHKA2 antibody

Catalog No. ABIN4904749

Product Details anti-PHKA2 Antibody

Target: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHKA2 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9A, also known as X-linked liver glycogenosis. Alternatively spliced transcript variants have been reported, but the full-length nature of these variants has not been determined.[provided by RefSeq, Feb 2010]

Purification: Affinity purification

Immunogen: Recombinant protein of human PHKA2.

Isotype: IgG

Application Details

Application Notes: WB 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for PHKA2

Target: PHKA2 (Phosphorylase Kinase, alpha 2 (PHKA2))

Alternative Name: PHKA2 (PHKA2 Products)

Synonyms: GSD9A antibody, PHK antibody, PYK antibody, PYKL antibody, XLG antibody, XLG2 antibody, PHKA2 antibody, 6330505C01Rik antibody, D330034O08 antibody, Phk antibody, phosphorylase kinase regulatory subunit alpha 2 antibody, phosphorylase kinase alpha 2 antibody, PHKA2 antibody, Phka2 antibody

Gene ID: 5256

UniProt: P46019

Pathways: Cellular Glucan Metabolic Process