NLRP3 antibody (AA 81-93)
-
- Target See all NLRP3 Antibodies
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
-
Binding Specificity
- AA 81-93
-
Reactivity
- Human, Monkey
-
Host
- Goat
-
Clonality
- Polyclonal
-
Conjugate
- This NLRP3 antibody is un-conjugated
-
Application
- ELISA
- Specificity
- Human NLRP3. This antibody is expected to recognize all reported isoforms (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Reported variants NP_001073289.1 and NP_004886.3 represent identical protein.
- Predicted Reactivity
- Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Panda, Bat, Pig (92%) Dog, Bovine, Rabbit (85%).
- Purification
- Immunoaffinity purified
- Immunogen
-
Synthetic peptide RDLYEKAKRDEPK-C from the N-terminus (near) of human NLRP3 (NP_004886.3, NP_899632.1, NP_001120933.1, NP_001120934.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Panda, Bat, Pig (92%), Dog, Bovine, Rabbit (85%).
Type of Immunogen: Synthetic peptide - Top Product
- Discover our top product NLRP3 Primary Antibody
-
-
- Application Notes
-
Approved: Peptide-ELISA (1:32000)
Usage: Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Preliminary experiments gave an approx 36 kDa band in Human Peripheral Blood Mononucleocytes lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the smallest calculated size of 106 kDa according to NP_899632.1. The 36 kDa band was successfully blocked by incubation with the immunizing peptide. - Comment
-
Target Species of Antibody: Human
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Tris-buffered saline, pH 7.3, 0.5 % BSA, 0.02 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Minimize freezing and thawing.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Avoid freeze-thaw cycles.
-
- Target
- NLRP3 (NLR Family, Pyrin Domain Containing 3 (NLRP3))
- Alternative Name
- NALP3 / NLRP3 (NLRP3 Products)
- Synonyms
- CIAS1 antibody, Nalp3 antibody, avp antibody, cias1 antibody, nalp3 antibody, pypaf1 antibody, agtavprl antibody, AGTAVPRL antibody, AII antibody, AVP antibody, C1orf7 antibody, CLR1.1 antibody, FCAS antibody, FCU antibody, MWS antibody, NALP3 antibody, PYPAF1 antibody, AII/AVP antibody, Cias1 antibody, Mmig1 antibody, Pypaf1 antibody, NLR family pyrin domain containing-like antibody, NLR family pyrin domain containing 3 antibody, NLR family, pyrin domain containing 3 L homeolog antibody, NLR family, pyrin domain containing 3 antibody, NLRPL antibody, NLRP3 antibody, nlrp3.L antibody, Nlrp3 antibody
- Background
-
Name/Gene ID: NLRP3
Synonyms: NLRP3, AGTAVPRL, AII, C1orf7, Caterpiller protein 1.1, Cryopyrin, FCAS, FCU, PYPAF1, NALP3, CIAS1, CLR1.1, MWS - Gene ID
- 114548
- NCBI Accession
- NP_004886, NP_899632, NP_001120933, NP_001120934
- UniProt
- Q96P20
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Inflammasome
-