Lactate Dehydrogenase A antibody (N-Term)
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- Target See all Lactate Dehydrogenase A (LDHA) Antibodies
- Lactate Dehydrogenase A (LDHA)
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Binding Specificity
- AA 1-332, N-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Lactate Dehydrogenase A antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- Specificity
- The antibody recognizes Human LDHA. Other species not tested.
- Characteristics
- Synonyms: LDH-A, L-lactate dehydrogenase A chain, LDH-M, PIG19, NY-REN-59, LDH muscle subunit,Cell proliferation-inducing gene 19 protein, Renal carcinoma antigen NY-REN-59
- Purification
- Affinity chromatography on Protein G
- Immunogen
- Recombinant human LDHA (1-332aa) purified from E. coli
- Clone
- AT1A4
- Isotype
- IgG2b
- Top Product
- Discover our top product LDHA Primary Antibody
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- Application Notes
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ELISA. Western blot (1: 500 - 1: 8000). Immunofluorescence (1: 500 - 1: 8000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS, pH 7.4, 0.09 % Sodium Azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C/-20 °C
- Storage Comment
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Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Expiry Date
- 12 months
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- Target
- Lactate Dehydrogenase A (LDHA)
- Alternative Name
- LDHA (LDHA Products)
- Synonyms
- GSD11 antibody, LDH1 antibody, LDHM antibody, LDH-M antibody, ldh-h antibody, ldha antibody, ldha-B antibody, ldhbb antibody, trg-5 antibody, Ldh1 antibody, Ldhm antibody, l7R2 antibody, gsd11 antibody, ldh-m antibody, ldh1 antibody, ldhm antibody, pig19 antibody, ldha1 antibody, ldhab antibody, LDH-A antibody, LDHC antibody, lactate dehydrogenase A antibody, lactate dehydrogenase B L homeolog antibody, lactate dehydrogenase A4 antibody, lactate dehydrogenase A L homeolog antibody, L-lactate dehydrogenase A chain antibody, LDHA antibody, ldhb.L antibody, Ldha antibody, ldha antibody, ldha.L antibody, LOC100713875 antibody
- Background
- Lactate through lactate dehydrogenase A (LDHA), which is encoded by a target gene of c-Myc and hypoxia-inducible factor (HIF-1). LDHA expression is repressed by SugR in the absence of sugar. Reduction of LDHA causes bioenergetic and oxidative stress leading to cell death. LDHA (LDH-5, M-LDH, or A4), which is the predominant form in skeletal muscle, kinetically favors the conversion of pyruvate to lactate. Therefore, LDH-A is an attractive target for cancer therapy since its expression is largely relegated to skeletal muscle.Synonyms: Cell proliferation-inducing gene 19 protein, L-lactate dehydrogenase A chain, LDH muscle subunit, LDH-A, LDH-M, NY-REN-59, PIG19, Renal carcinoma antigen NY-REN-59
- Gene ID
- 3939
- UniProt
- P00338
- Pathways
- Warburg Effect
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