DLG2 antibody (N-Term)

Catalog No. ABIN492455

Product Details anti-DLG2 Antibody

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Binding Specificity: AA 1-852, N-Term

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This DLG2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Specificity: Detects ~110 kDa protein. No cross-reactivity against other MAGUK family members PSD95, SAP97, SAP102 expressed in transfected cells.

Characteristics: Synonyms: Disks large homolog 2, PSD-93, Chapsyn-110, Postsynaptic density protein PSD-93,Channel-associated protein of synapse-110

Purification: Protein G Chromatography.

Immunogen: Fusion protein amino acids 1-852 of Rat Chapsyn-110 (Accession number Q63622).

Clone: S18-30

Isotype: IgG1

Application Details

Application Notes: Western blot: 1 μg/mL1 μg/mL was sufficient for detection of Chapsyn-110 in 10 μg of rat brain lysate bycolorimetric immunoblot analysis using Goat anti-mouse IgG: HRP as the secondaryantibody. Immunoprecipitation.1.0-10 μg/mLImmunofluorescence: 1.0-10 μg/mLImmunocytochemistry: 0.1-1.0 μg/mLImmunohistochemistry: 0.1-1.0 μg/mL
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 50 % Glycerol as stabilizer and 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for DLG2

Target: DLG2 (Discs, Large Homolog 2 (DLG2))

Alternative Name: DLG2 / PSD93 (DLG2 Products)

Synonyms: PPP1R58 antibody, PSD-93 antibody, PSD93 antibody, chapsyn-110 antibody, A330103J02Rik antibody, B230218P12Rik antibody, B330007M19Rik antibody, Dlgh2 antibody, Gm1197 antibody, discs, large homolog 2 (Drosophila) antibody, discs large MAGUK scaffold protein 2 antibody, dlg2 antibody, DLG2 antibody, Dlg2 antibody

Background: Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80 % identical to PSD-95/SAP90 and SAP97 (1). It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins (1, 2).Synonyms: Channel-associated protein of synapse-110, Chapsyn-110, Disks large homolog 2, PSD-93, Postsynaptic density protein PSD-93

Gene ID: 64053

UniProt: Q63622