Post-GPI Attachment To Proteins 3 (PGAP3) (C-Term) antibody

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Antigen
  • GB10206
  • AGLA546
  • CAB2
  • PER1
  • PERLD1
  • PP1498
  • D430035D22Rik
  • Perld1
  • perld1
  • pgap3
  • post-GPI attachment to proteins factor 3
  • post-GPI attachment to proteins 3
  • per1-like domain containing 1
  • zgc:171485
  • LOC412085
  • PGAP3
  • Perld1
  • Pgap3
  • pgap3
  • zgc:171485
Alternatives
anti-Human Post-GPI Attachment To Proteins 3 antibody for Dot Blot
Epitope
C-Term
14
12
10
7
6
4
3
2
2
2
2
1
Reactivity
Human
45
5
4
4
3
3
3
2
2
2
1
1
Host
Rabbit
45
Clonality
Polyclonal
Conjugate
Un-conjugated
6
6
2
2
2
2
Application
Dot Blot (DB), Enzyme Immunoassay (EIA), Western Blotting (WB)
42
27
22
14
12
5
2
1
1
Options
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Immunogen Synthetic peptide corresponding to c-terminal of MGC9753 protein
Sequence CEI EIN GQL VFS KLE NGG F
Specificity This antibody detects CAB2 / MGC9753 at C-term.
Cross-Reactivity (Details) Species reactivity (tested):Human
Purification Affinity chromatography
Alternative Name PGAP3 (PGAP3 Antibody Abstract)
Background Certain loci on human chromosome 17q12 are frequently amplified in various types of cancers. One of such loci is PP1R1B-ERBB2-GRB7 which is greatly amplified in gastric and breast cancer. Search of other genes that reside close to this recombination hot spot or Synonyms: CAB2, COS16 homolog, Gene coamplified with ERBB2 protein, PER1-like domain-containing protein 1, PERLD1, Post-GPI attachment to proteins factor 3
Gene ID 93210
NCBI Accession NP_219487
UniProt Q96FM1
Research Area Organelles
Pathways Inositol Metabolic Process
Application Notes Dor blot: 1: 15,000-1: 20,000. ELISA: 1: 15,000-1: 20,000. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 0.5 - 0.75 mg/mL
Buffer Stabilization buffer
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Store (in aliquots) at -20 °C.
Background publications Katoh, Katoh: "Identification and characterization of mouse Erbb2 gene in silico." in: International journal of oncology, Vol. 23, Issue 3, pp. 831-5, 2003 (PubMed).

Katoh, Katoh: "MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain." in: International journal of oncology, Vol. 22, Issue 6, pp. 1369-74, 2003 (PubMed).

Kauraniemi, Kuukasjärvi, Sauter, Kallioniemi: "Amplification of a 280-kilobase core region at the ERBB2 locus leads to activation of two hypothetical proteins in breast cancer." in: The American journal of pathology, Vol. 163, Issue 5, pp. 1979-84, 2003 (PubMed).