GRIN3B
Reactivity: Human
WB, ELISA, IHC
Host: Rabbit
Polyclonal
HRP
Application Notes
Peptide ELISA: Detection Limit: 1/8000. Western blot: 0.5-1.5 μg/mL. Detects a band of Approx 110 kDa in Human Brain (Cerebellum and Cerebral Cortex) lysates. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Add. Information: Calculated Molecular Weight: 110 kDa according to NP_619635.1
Restrictions
For Research Use only
Concentration
0.5 mg/mL
Buffer
Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
NR3B is a NMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. NR3B is found in a complex containing GRIN1 and GRIN2A at the cell membrane. NR3B requires the presence of GRIN1 to be targeted at the cell membrane. NR3B is expressed in the hippocampus, corpus callosum, as well as the facial and trigeminal nuclei of the brainstem and the ventral horn of the spinal cord.Synonyms: Glutamate [NMDA] receptor subunit 3B, NMDAR3B, NR3B