PFDN1 antibody

Catalog No. ABIN498299

Product Details anti-PFDN1 Antibody

Target: PFDN1 (Prefoldin Subunit 1 (PFDN1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFDN1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of Prefoldin 1 protein. (region surrounding Glu35)

Cross-Reactivity (Details): Species reactivity (expected):Mouse.
Species reactivity (tested):Human.

Purification: Affinity-chromatography using epitope-specific immunogen

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PFDN1

Target: PFDN1 (Prefoldin Subunit 1 (PFDN1))

Alternative Name: PFDN1 (PFDN1 Products)

Synonyms: PFDN1 antibody, 2700086I23Rik antibody, AA408327 antibody, AU044714 antibody, PDF antibody, PFD1 antibody, zgc:110742 antibody, prefoldin subunit 1 antibody, prefoldin 1 antibody, prefoldin subunit 1 S homeolog antibody, PFDN1 antibody, AFUA_4G12360 antibody, pfdn1 antibody, Pfdn1 antibody, pfdn1.S antibody

Background: PFDN1 is a heterohexameric chaperone protein which assists in the correct folding of other proteins. It binds specifically to cytosolic chaperonin and transfers target proteins. PFDN1 may function by selectively targeting nascent actin and tubulin chains pending their transfer to cytosolic chaperonin for final folding and/or assembly. It promotes folding in an environment in which there are many competing pathways for non native proteins.Synonyms: PFD1, Prefoldin subunit 1

Molecular Weight: approx. 14 kDa

Gene ID: 5201

NCBI Accession: NP_002613

UniProt: O60925

Pathways: Unfolded Protein Response