SKIL antibody
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- Target See all SKIL Antibodies
- SKIL (SKI-Like Oncogene (SKIL))
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Reactivity
- Human, Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This SKIL antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of SnoN protein. (region surrounding Asp652)
- Cross-Reactivity (Details)
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Species reactivity (expected):Mouse.
Species reactivity (tested):Human. - Purification
- Affinity chromatography using epitope-specific immunogen
- Purity
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product SKIL Primary Antibody
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- Application Notes
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Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Target
- SKIL (SKI-Like Oncogene (SKIL))
- Alternative Name
- SKIL / SnoN (SKIL Products)
- Synonyms
- SNO antibody, SnoA antibody, SnoI antibody, SnoN antibody, Skir antibody, Sno antibody, SKIL antibody, DKFZp459L122 antibody, sno antibody, zgc:193698 antibody, SKI like proto-oncogene antibody, SKI-like proto-oncogene antibody, ski-like protein antibody, SKI-like antibody, SKI-like proto-oncogene b antibody, SKIL antibody, Skil antibody, LOC100010058 antibody, skil antibody, skilb antibody
- Background
- SnoN may have a regulatory role in cell division or differentiation in response to extracellular signals. SnoN acts as a positive mediator of TGF beta induced transcription and cell cycle arrest in lung epithelial cells. The ability of SnoN to repress the growth inhibitory function of the Smad proteins is required for their transforming activity.Synonyms: SNO, Ski-like protein, Ski-related novel protein N, Ski-related oncogene, Ski-related protein, SnoA, Snol
- Molecular Weight
- approx. 77 kDa
- Gene ID
- 6498
- NCBI Accession
- NP_001138569
- UniProt
- P12757
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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