CKMT2 antibody
-
- Target See all CKMT2 Antibodies
- CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))
-
Reactivity
- Human, Mouse, Rat
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This CKMT2 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of sMtCK protein. (region surrounding Trp262)
- Cross-Reactivity (Details)
-
Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. - Purification
- Affinity chromatography using epitope-specific immunogen
- Purity
- > 95 % (by SDS-PAGE)
- Top Product
- Discover our top product CKMT2 Primary Antibody
-
-
- Application Notes
-
Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
-
- Concentration
- 1.0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
- Target
- CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))
- Alternative Name
- CKMT2 (CKMT2 Products)
- Synonyms
- 2300008A19Rik antibody, ScCKmit antibody, MIBCK antibody, SMTCK antibody, ckmt2-2 antibody, zgc:73059 antibody, CKMT2 antibody, Mib-CK antibody, S-MtCK antibody, creatine kinase, mitochondrial 2 antibody, creatine kinase, mitochondrial 2 (sarcomeric) antibody, creatine kinase, mitochondrial 2b (sarcomeric) antibody, CKMT2 antibody, ckmt2 antibody, Ckmt2 antibody, ckmt2b antibody
- Background
- CKMT2 belongs to the creatine kinase isoenzyme family, and is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It exists as two isoenzymes, sarcomeric CKMT2 and ubiquitous CKMT2, which are encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.Synonyms: Basic-type mitochondrial creatine kinase, Creatine kinase S, Mib-CK, S-MtCK, sarcomeric mitochondrial Creatine kinase
- Molecular Weight
- approx. 45 kDa
- Gene ID
- 1160
- NCBI Accession
- NP_001093205
- UniProt
- P17540
-