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CKMT2 antibody

CKMT2 Reactivity: Human, Mouse, Rat WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN498310
  • Target See all CKMT2 Antibodies
    CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))
    Reactivity
    • 63
    • 39
    • 25
    • 9
    • 8
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 57
    • 7
    Rabbit
    Clonality
    • 58
    • 6
    Polyclonal
    Conjugate
    • 37
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CKMT2 antibody is un-conjugated
    Application
    • 57
    • 38
    • 13
    • 9
    • 7
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of sMtCK protein. (region surrounding Trp262)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography using epitope-specific immunogen
    Purity
    > 95 % (by SDS-PAGE)
    Top Product
    Discover our top product CKMT2 Primary Antibody
  • Application Notes
    Western blot: 1: 500 - 1: 1000. Immunohistochemistry on paraffin sections: 1: 50 - 1: 200. Immunoflourescence: 1: 50 - 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    CKMT2 (Creatine Kinase, Mitochondrial 2 (Sarcomeric) (CKMT2))
    Alternative Name
    CKMT2 (CKMT2 Products)
    Synonyms
    2300008A19Rik antibody, ScCKmit antibody, MIBCK antibody, SMTCK antibody, ckmt2-2 antibody, zgc:73059 antibody, CKMT2 antibody, Mib-CK antibody, S-MtCK antibody, creatine kinase, mitochondrial 2 antibody, creatine kinase, mitochondrial 2 (sarcomeric) antibody, creatine kinase, mitochondrial 2b (sarcomeric) antibody, CKMT2 antibody, ckmt2 antibody, Ckmt2 antibody, ckmt2b antibody
    Background
    CKMT2 belongs to the creatine kinase isoenzyme family, and is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It exists as two isoenzymes, sarcomeric CKMT2 and ubiquitous CKMT2, which are encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Sarcomeric mitochondrial creatine kinase has 80 % homology with the coding exons of ubiquitous mitochondrial creatine kinase. This gene contains sequences homologous to several motifs that are shared among some nuclear genes encoding mitochondrial proteins and thus may be essential for the coordinated activation of these genes during mitochondrial biogenesis. Three transcript variants encoding the same protein have been found for this gene.Synonyms: Basic-type mitochondrial creatine kinase, Creatine kinase S, Mib-CK, S-MtCK, sarcomeric mitochondrial Creatine kinase
    Molecular Weight
    approx. 45 kDa
    Gene ID
    1160
    NCBI Accession
    NP_001093205
    UniProt
    P17540
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