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PER3 antibody

PER3 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN498324
  • Target See all PER3 Antibodies
    PER3 (Period Homolog 3 (PER3))
    Reactivity
    • 50
    • 29
    • 14
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 45
    • 6
    Rabbit
    Clonality
    • 46
    • 5
    Polyclonal
    Conjugate
    • 26
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This PER3 antibody is un-conjugated
    Application
    • 39
    • 21
    • 13
    • 13
    • 10
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of Per3 protein. (region surrounding Pro2)
    Cross-Reactivity (Details)
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product PER3 Primary Antibody
  • Application Notes
    Western blot 1/500-1/1000. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    PER3 (Period Homolog 3 (PER3))
    Alternative Name
    PER3 (PER3 Products)
    Synonyms
    period3 antibody, rper3 antibody, GIG13 antibody, 2810049O06Rik antibody, mPer3 antibody, period circadian clock 3 antibody, period circadian regulator 3 antibody, Per3 antibody, PER3 antibody
    Background
    Biological timepieces called circadian clocks are responsible for the regulation of hormonal rhythms, sleep cycles and other behaviors. The superchiasmatic nucleus (SCN), which is located in the brain, was the first mammalian circadian clock to be discovered. A number of transcription factors appearing to be molecular components of the SCN clock have been identified. Mutations within the Clock gene increase the length of the endogenous period and cause a loss of rhythmicity of circadian oscillations. Three mammalian period proteins, designated Per1, Per2 and Per3, exhibit circadian rhythyms in the SCN.During subjective night, Per1 and Per2 RNA levels increase in response to light pulses while Per3 RNA levels show no change in response to light pulses. Tim, for timeless, interacts with Per1 as well as Per2, and Tim and Per1 negatively regulate Clock-BMAL1-induced transcription.Synonyms: Cell growth-inhibiting gene 13 protein, Circadian clock protein PERIOD 3, GIG13, Period circadian protein homolog 3, hPER3
    Molecular Weight
    approx. 43 kDa
    Gene ID
    8863
    NCBI Accession
    NP_058515
    UniProt
    P56645
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