BCL2L2 antibody

Catalog No. ABIN498448

Product Details anti-BCL2L2 Antibody

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCL2L2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Bcl-w protein. (region surrounding Gly154)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for BCL2L2

Target: BCL2L2 (BCL2-Like 2 (BCL2L2))

Alternative Name: Bcl-2-Like 2 (BCL2L2 Products)

Synonyms: bcl2l2 antibody, BCL2L2 antibody, BCL-W antibody, BCL2-L-2 antibody, BCLW antibody, PPP1R51 antibody, AW048834 antibody, Bcl-w antibody, Gtrgal2 antibody, Gtrosa41 antibody, bclw antibody, c98 antibody, BCL-WEL antibody, BCL-WS antibody, Bclw antibody, bcl-w antibody, bcl2l2-a antibody, bcl2l2-b antibody, xr1 antibody, BCL2 like 2 antibody, BCL2-like 2 antibody, BCL2 like 12 antibody, Bcl2-like 2 antibody, bcl-2-like protein 2 antibody, BCL2-like 2 L homeolog antibody, BCL2L2 antibody, bcl2l2 antibody, BCL2L12 antibody, Bcl2l2 antibody, LOC100154044 antibody, LOC100345100 antibody, bcl2l2.L antibody

Background: The Bcl-2 family of proteins is characterized by its ability to modulate cell death (apoptosis) under a broad range of physiological conditions. Bcl-2, A1 and Bcl-xL function to inhibit apoptosis while other members of the Bcl-2 family, Bax, Bad, Bak and Bcl-xS oppose their death-suppressing effects. Using a PCR-based strategy, an additional protein with life-promoting activity, designated Bcl-w, has been identified. The protein is highly conserved between mouse and human and is encoded by a gene located near the TCRalpha gene on chromosome 14. Bcl-w is expressed in myeloid cell lines but not in T and B lymphocytes, and can be found in a wide range of tissues. An alternative splicing event in exon 4 results in two transcripts. The first, Bcl-w, encodes a protein of 193 amino acids, and the second, Bcl-w/rox, encodes a protein 333 amino acids in length. The Synonyms: BCL2L2, BCLW, Bcl-w, Bcl2-L-2, KIAA0271

Molecular Weight: approx. 21 kDa

Gene ID: 599

NCBI Accession: NP_004041

UniProt: Q92843