NME1 antibody (Non-Metastatic Cells 1, Protein (NM23A) Expressed in)

Details for Product anti-NME1 Antibody No. ABIN498563, Supplier: Log in to see
Antigen
  • NDK I
  • NDPK I
  • NME1
  • NME1-NME2
  • AWD
  • GAAD
  • NB
  • NBS
  • NDKA
  • NDPK-A
  • NDPKA
  • NM23
  • NM23-H1
  • AL024257
  • NM23-M1
  • NM23A
  • ndpk-b
  • ndpkb
  • nm23-h2
  • nm23b
  • nm23ndk
  • nme1
  • puf
  • nm23ndk-a
  • nme2
  • NDPK-Z1
  • NM23-B
  • NM23-Z1
  • ndpkz1
  • nme2b1
  • NM23-C1
  • NBR-A
  • NBR-B
  • NME1-1
  • T30A10.80
  • T30A10_80
  • CHH
  • RMRPR
  • RRP2
  • nucleoside diphosphate kinase
  • non-metastatic cells 1, protein (NM23A) expressed in
  • NME/NM23 nucleoside diphosphate kinase 1
  • NME/NM23 nucleoside diphosphate kinase 2
  • NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1
  • nucleoside diphosphate kinase 1
  • RNA component of mitochondrial RNA processing endoribonuclease
  • LOC547870
  • NME1
  • Nme1
  • nme2-b
  • nme2-a
  • nme2b.1
  • NDPK1
  • RMRP
Alternatives
anti-Human NME1 antibody for Immunohistochemistry (Paraffin-embedded Sections)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
292
53
50
14
9
8
6
4
4
3
3
2
2
1
1
Host
Rabbit
145
142
6
2
2
Clonality
Polyclonal
Conjugate
This NME1 antibody is un-conjugated
12
12
8
7
6
6
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
250
125
88
63
40
15
13
12
10
7
6
2
2
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Specificity This antibody detects endogenous levels of NM23-H1 protein. (region surrounding Tyr52)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification Affinity chromatography
Purity > 95 % by SDS-PAGE
Alternative Name NDP Kinase A (NME1 Antibody Abstract)
Background The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sublines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and -H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nucleasehypersensitive elements at positions 142 to 115 of the human c-Myc promotor.Synonyms: GAAD, Granzyme A-activated DNase, NDPKA, NM23, NME1, Nucleoside diphosphate kinase A, nm23-H1
Molecular Weight approx. 20 kDa
Gene ID 4830
NCBI Accession NP_000260
UniProt P15531
Research Area Kinases/Phosphatases, Cancer, Transcription Factors
Pathways Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process
Application Notes Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody (ABIN498563) Immunohistochemistry (IHC) analyzes of NM23-H1 antibody in paraffin-embedded h...
Western Blotting (WB) image for anti-Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1) antibody (ABIN498563) Western blot (WB) analysis of NM23-H1 antibody in extracts from HeLa cells.
Did you look for something else?