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Netrin 1 antibody
NTN1
Reactivity: Human, Mouse, Rat
WB, IHC (p)
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Netrin 1 Antibody
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Target
See all Netrin 1 (NTN1) Antibodies
Netrin 1 (NTN1)
Reactivity
All reactivities for Netrin 1 antibodies
Human, Mouse, Rat
Host
All hosts for Netrin 1 antibodies
Rabbit
Clonality
All clonalities for Netrin 1 antibodies
Polyclonal
Conjugate
All conjugates for Netrin 1 antibodies
This Netrin 1 antibody is un-conjugated
Application
All applications for Netrin 1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificity
This antibody detects endogenous levels of Netrin-1 protein. (region surrounding Gln533)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity Chromatography using epitope-specific immunogen
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Alternatives
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Application Details
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Application Notes
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for Netrin 1
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Target
Netrin 1 (NTN1)
Alternative Name
Netrin-1 (NTN1 Products )
Synonyms
ntn1-A antibody, Netrin-1 antibody, NTN1 antibody, unc-6 antibody, MGC147073 antibody, NTN1L antibody, AI561871 antibody, BC019633 antibody, netrin-1 antibody, netrin 1 L homeolog antibody, netrin 1 antibody, ntn1.L antibody, NTN1 antibody, ntn1 antibody, Ntn1 antibody
Background
Netrin-G1 ligand (NGL1) is a transmembrane protein containing leucine-rich repeat (LRR) and immunoglobulin (Ig) domains that specifically interact with netrin-G1 through its LRR region. Whereas netrin-G1 is expressed highly in mouse thalamic axons, NGL1 is most abundant in the striatum and the cerebral cortex. NGL1 is implicated in facilitating axonal growth of the vertebrate CNS. Membrane-bound netrin-G1 acts as an axonal receptor, whereas the LRR-containing transmembrane protein NGL1 acts as a ligand in promoting the growth of thalamic axons.Synonyms: NTN1, NTN1L
Molecular Weight
approx. 68 kDa
Gene ID
9423
NCBI Accession
NP_004813
UniProt
O95631
Pathways
Regulation of Cell Size
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