Kv3.4 antibody

Catalog No. ABIN498996

Product Details anti-Kv3.4 Antibody

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kv3.4 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Kv3.4 protein. (region surrounding Arg11)

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000. Immunohistochemistry: 1/50 - 1/200. Immunofluorescence: 1/50 - 1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Kv3.4

Target: Kv3.4 (KCNC4) (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 4 (KCNC4))

Alternative Name: KCNC4 (KCNC4 Products)

Synonyms: C1orf30 antibody, HKSHIIIC antibody, KSHIIIC antibody, KV3.4 antibody, AI850292 antibody, Kcr2-4 antibody, Kv3.4 antibody, potassium voltage-gated channel subfamily C member 4 antibody, potassium channel, voltage gated Shaw related subfamily C, member 4 antibody, potassium voltage gated channel, Shaw-related subfamily, member 4 antibody, KCNC4 antibody, kcnc4 antibody, Kcnc4 antibody

Background: KCNC4 (Potassium voltage gated channel subfamily C member 4) belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.Synonyms: KSHIIIC, Potassium voltage-gated channel subfamily C member 4, Voltage-gated potassium channel subunit Kv3.4

Molecular Weight: approx. 70 kDa

Gene ID: 3749

NCBI Accession: NP_001034663

UniProt: Q03721