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MAP2K7 antibody
MAP2K7
Reactivity: Human, Mouse, Rat
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-MAP2K7 Antibody
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Target
See all MAP2K7 Antibodies
MAP2K7
(Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
Reactivity
All reactivities for MAP2K7 antibodies
Human, Mouse, Rat
Host
All hosts for MAP2K7 antibodies
Rabbit
Clonality
All clonalities for MAP2K7 antibodies
Polyclonal
Conjugate
All conjugates for MAP2K7 antibodies
This MAP2K7 antibody is un-conjugated
Application
All applications for MAP2K7 antibodies
Western Blotting (WB)
Specificity
This antibody detects endogenous levels of MEK-7 protein. (region surrounding Ile264)
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Affinity chromatography
Purity
> 95 % by SDS-PAGE
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Discover our top product MAP2K7 Primary Antibody
Alternatives
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Application Details
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Application Notes
Western Blot: 1/500 - 1/1000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1,0 mg/mL
Buffer
Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Target Details for MAP2K7
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Target
MAP2K7
(Mitogen-Activated Protein Kinase Kinase 7 (MAP2K7))
Alternative Name
MAP2K7 (MAP2K7 Products )
Synonyms
MAP2K7 antibody, 2 antibody, JNKK antibody, Jnkk2 antibody, Mapkk7 antibody, Mek7 antibody, Mkk7 antibody, MAPKK7 antibody, MKK7 antibody, PRKMK7 antibody, SAPKK-4 antibody, SAPKK4 antibody, 5930412N11Rik antibody, JNKK 2 antibody, MAPKK 7 antibody, MEK 7 antibody, Prkmk7 antibody, sek2 antibody, si:ch211-254d18.2 antibody, map2k7-A antibody, mitogen-activated protein kinase kinase 7 antibody, mitogen activated protein kinase kinase 7 antibody, mitogen-activated protein kinase kinase 7 L homeolog antibody, MAP2K7 antibody, Map2k7 antibody, map2k7 antibody, map2k7.L antibody
Background
Mitogen Activated Protein Kinase Kinase 7 (MEK 7 or MKK 7) is a 38 kDa member of a tyrosine/threonine protein kinase family that activates the c Jun NH2-terminal kinases (JNK), which is part of the inflammation/stress signaling pathway. Phosphorylation of MEK 7 by MEKK 1 on serine 271 and threonine 275 in the catalytic domain activates the protein and enables MEK 7 to phosphorylate JNK.Synonyms: Dual specificity mitogen-activated protein kinase kinase 7, JNK-activating kinase 2, MAP kinase kinase 7, MAPK/ERK kinase 7, MAPKK 7, MEK7, MKK7, NKK2, c-Jun N-terminal kinase kinase 2
Molecular Weight
approx. 48 kDa
Gene ID
5609
NCBI Accession
NP_660186
UniProt
O14733
Pathways
MAPK Signaling , TLR Signaling , Fc-epsilon Receptor Signaling Pathway , Activation of Innate immune Response , Toll-Like Receptors Cascades , BCR Signaling
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