CLDN8 antibody

Catalog No. ABIN499047

Product Details anti-CLDN8 Antibody

Target: CLDN8 (Claudin 8 (CLDN8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLDN8 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of Claudin-8 protein. (region surrounding Ile118)

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Affinity chromatography

Purity: > 95 % by SDS-PAGE

Application Details

Application Notes: Western Blot: 1/500 - 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CLDN8

Target: CLDN8 (Claudin 8 (CLDN8))

Alternative Name: Claudin-8 / CLDN8 (CLDN8 Products)

Synonyms: zgc:91900 antibody, wu:fa01e05 antibody, CLDN8 antibody, AI648025 antibody, claudin 8 antibody, CLDN8 antibody, cldn8 antibody, Cldn8 antibody

Background: Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-8 is a multi-pass membrane protein that belongs to the claudin family. Localized to the caput and the lateral margins of principal cells, claudin-8 plays an important role in tight junction-specific obliteration of the intercellular space.Synonyms: PRO1573, UNQ779

Molecular Weight: approx. 28 kDa

Gene ID: 9073

NCBI Accession: NP_955360

UniProt: P56748

Pathways: Hepatitis C