GAS1 antibody

Catalog No. ABIN499084

Product Details anti-GAS1 Antibody

Target: GAS1 (Growth Arrest-Specific 1 (GAS1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GAS1 antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: This antibody detects endogenous levels of Gas1 protein. (region surrounding Arg274)

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: Affinity Chromatography using epitope-specific immunogen.

Application Details

Application Notes: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for GAS1

Target: GAS1 (Growth Arrest-Specific 1 (GAS1))

Alternative Name: GAS1 (GAS1 Products)

Synonyms: AW554192 antibody, Gas-1 antibody, MGC147541 antibody, id:ibd5013 antibody, wu:fa11f02 antibody, wu:faa26f09 antibody, im:7428747 antibody, wu:fc54h12 antibody, zgc:153938 antibody, growth arrest specific 1 antibody, growth arrest-specific 1 antibody, growth arrest-specific 1a antibody, growth arrest-specific 1b antibody, GAS1 antibody, Gas1 antibody, gas1 antibody, gas1a antibody, gas1b antibody

Background: Growth arrest specific proteins, including Gas1 and Gas6, are activated in quiescent cells. Gas 1-induced growth arrest is mediated by p53, and Gas1 appears to be able to suppress tumor cell growth. Gas6, a ligand for the tyrosine kinase receptor Axl, was initially identified as a member of the vitamin K-dependent protein family and exhibits a high degree of amino acid sequence homology to protein S, a negative co-regulator in the coagulation pathway.Synonyms: GAS-1, Growth arrest-specific protein 1

Molecular Weight: approx. 36 kDa

Gene ID: 2619

NCBI Accession: NP_002039

UniProt: P54826