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TIAL1 antibody (Internal Region)

TIAL1 Reactivity: Human, Mouse, Dog, Cow WB, IHC (p), EIA Host: Goat Polyclonal unconjugated
Catalog No. ABIN499121
  • Target See all TIAL1 Antibodies
    TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
    Binding Specificity
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 26
    • 14
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Dog, Cow
    Host
    • 21
    • 4
    • 1
    Goat
    Clonality
    • 24
    • 2
    Polyclonal
    Conjugate
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIAL1 antibody is un-conjugated
    Application
    • 13
    • 9
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Sequence
    C-SPEITTEDIK SAFAP
    Specificity
    This antibody is expected to recognize both isoforms (NP_003243.1, NP_001029097.1).
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Canine, Bovine.
    Species reactivity (tested):Human.
    Purification
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the Internal region of Human TIAL1 (NP_003243.1 and NP_001029097.1) Genename: TIAL1
    Top Product
    Discover our top product TIAL1 Primary Antibody
  • Application Notes
    Peptide ELISA: Limit Dilution: 1/64000. Western blot: 1-3 μg/mL. Approx 45 kDa band observed in lysates of cell line K562.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    TIAL1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein-Like 1 (TIAL1))
    Alternative Name
    TIAL1 (TIAL1 Products)
    Synonyms
    TCBP antibody, TIAR antibody, 5330433G13Rik antibody, AL033329 antibody, mTIAR antibody, zgc:66130 antibody, tcbp antibody, tiar antibody, TIA1 cytotoxic granule associated RNA binding protein like 1 antibody, Tia1 cytotoxic granule-associated RNA binding protein-like 1 antibody, TIA1 cytotoxic granule-associated RNA binding protein-like 1 antibody, TIAL1 antibody, Tial1 antibody, tial1 antibody
    Background
    TIA1 is a member of an RNA binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing.Synonyms: Nucleolysin TIAR, TIA-1-related protein
    Molecular Weight
    43.4 kDa (NP_001029097.1)
    Gene ID
    7073
    NCBI Accession
    NP_003243
    UniProt
    Q01085
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