ALDH3A1 antibody (C-Term)

Catalog No. ABIN499263

Product Details anti-ALDH3A1 Antibody

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH3A1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to ALDH3A1.

Purification: Affinity chromatography purified via peptide column

Immunogen: Aldh3A1 antibody was raised against a 13 amino acid peptide near the carboxy terminus of the human Aldh3A1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: Aldh3A1 antibody can be used for detection of Aldh3A1 at 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for ALDH3A1

Target: ALDH3A1 (Aldehyde Dehydrogenase 3 Family, Member A1 (ALDH3A1))

Alternative Name: ALDH3 (ALDH3A1 Products)

Synonyms: ALDC antibody, ALDH-E1 antibody, ALDH1 antibody, ALDH11 antibody, PUMB1 antibody, RALDH1 antibody, ALDH3 antibody, ALDHIII antibody, Ahd-4 antibody, Ahd4 antibody, Aldh antibody, Aldh3 antibody, AHDC antibody, Ahd-c antibody, aldehyde dehydrogenase 1 family member A1 antibody, aldehyde dehydrogenase 3 family member A1 antibody, aldehyde dehydrogenase antibody, aldehyde dehydrogenase, dimeric NADP-preferring antibody, aldehyde dehydrogenase family 3, subfamily A1 antibody, aldehyde dehydrogenase 3 family, member A1 antibody, ALDH1A1 antibody, ALDH3A1 antibody, OE_RS03630 antibody, LOC100077088 antibody, CLL_A1665 antibody, LOC100281700 antibody, LOC100285809 antibody, Aldh3a1 antibody

Background: Aldh3A1 is a member of the aldehyde dehydrogenase superfamily, a group of NAD(P)(+)-dependent enzymes that catalyze the oxidation of a wide spectrum of aliphatic and aromatic aldehydes. Aldh3A1 is highly expressed in stomach and even more strongly in cornea, representing between 5 to 50 % of the water soluble protein fraction in mammalian corneas. It is thought that Aldh3A1 acts to protect the cornea from UV-induced oxidative stress by not only detoxification of reactive aldehydes by also through the direct absorbtion of UV energy. However, corneas from Aldh3A1-null mice are indistinguishable from those from wild-type mice, mice lacking both Aldh3A1 and Aldh1A1 showed increased cataract formation following UVB exposure, suggesting that Aldh1A1 may be able to compensate for the loss of Aldh3A1. At least two isoforms of Aldh3A1 are known to exist. This antibody is predicted to have no cross-reactivity to Aldh3A2.Synonyms: ALDH3A1, ALDHIII, Aldehyde dehydrogenase, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, dimeric NADP-preferring

Gene ID: 218

NCBI Accession: NP_000682

UniProt: P30838