Influenza A H5N1 (Middle Region) antibody

Details for Product No. ABIN499391
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Middle Region
(9), (4), (3), (3), (2)
Influenza A Virus H5N1
(22), (9), (4)
(35), (9), (5), (5), (1), (1), (1)
Pubmed 1 reference available
Quantity 0.1 mg
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Catalog No. ABIN499391
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Immunogen Avian Influenza Nonstructural Protein 2 antibody was raised against a synthetic peptide corresponding to 14 amino acids near the middle of the Avian Influenza Nonstructural Protein 2 protein. Efforts were made to use relatively conserved regions of the viral sequence as the antigen.
Isotype IgG
Specificity This antibody reacts to Avian Influenza Nonstructural Protein 2.
Purification Affinity chromatography purified via peptide column
Background Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however, it is in birds that all subtypes, including the so-called “avian flu” or H5N1, can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. One of the less studied proteins encoded by the influenza virus is the nonstructural protein (NS) 2. NS2 binds to the influenza matrix protein M1 that is bound to the ribonucleoprotein (RNP) complex and mediates the contact between the M1/RNP complex and the cellular exportin CRM, but does not interact with nucleosomes.
Alternate names: Avian Influenza A H5N1 H5 Hemagglutinin
Application Notes Avian Influenza Nonstructural Protein 2 antibody can be used for the detection of the AvianInfluenza Nonstructural Protein 2 protein from influenza A in ELISA. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Thompson, Shay, Weintraub et al.: "Mortality associated with influenza and respiratory syncytial virus in the United States." in: JAMA : the journal of the American Medical Association, Vol. 289, Issue 2, pp. 179-86, 2003 (PubMed).

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