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B-Cell Receptor-Associated Protein 31 (BCAP31) (C-Term) antibody

Details for Product No. ABIN499417, Supplier: Log in to see
Antigen
  • 6c6-ag
  • bap31
  • cdm
  • dxs1357e
  • BCAP31
  • Bap31
  • 6C6-AG
  • BAP31
  • CDM
  • DXS1357E
  • CALD1
  • caldesmon
  • si:bz30i22.4
  • si:rp71-30i22.4
  • zgc:56389
Epitope
C-Term
33
15
7
6
4
3
3
3
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
130
32
30
5
4
2
2
1
1
1
1
Host
Rabbit
94
18
11
8
Clonality
Polyclonal
Conjugate
Un-conjugated
7
7
7
2
2
2
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
122
68
41
20
11
11
8
4
2
2
1
1
1
1
1
Supplier
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Immunogen Human BAP31 (C-Terminus) Peptide
Isotype IgG
Specificity BAP31 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human BAP31.
Purification Affinity chromatography purified via peptide column
Alternative Name BCAP31 / BAP31 (BCAP31 Antibody Abstract)
Background Bap31 and the related protein Bap29 are endoplasmic reticulum (ER) and ER-vesicle membrane proteins and members of the B-cell receptor-associated protein family (1,2). These two proteins are highly homologous and can form homo- and heterodimers. Bap31 is thought to be involved in the intracellular trafficking of several molecules such as MHC Class I molecules and CD11b/CD18 (3,4). It may also play a role in the initiation of ER stress-induced apoptosis through its association with caspase-8 via a death effector domain in its cytoplasmic tail, possibly through the promotion of membrane fragmentation and the release of cytochrome c from mitochondria (5). Bap31 itself contains two caspase cleavage sites and is cleaved during apoptosis. The p20 fragment of Bap31, when expressed ectopicially, is also a potent inducer cell death (5).Synonyms: 6C6-AG tumor-associated antigen, B-cell receptor-associated protein 31, BCR-associated protein Bap31, DXS1357E, Protein CDM, p28 Bap31
Gene ID 10134
NCBI Accession NP_005736
UniProt P51572
Application Notes ELISA. Western Blot. BAP31 antibody can be used for the detection of BAP31 at 0.5 - 1 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.
Supplier Images
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-B-Cell Receptor-Associated Protein 31 (BCAP31) (C-Term) antibody (ABIN499417) Immunohistochemistry of BAP31 in rat lung tissue with BAP31 antibody at 2 μg/ml.
Western Blotting (WB) image for anti-B-Cell Receptor-Associated Protein 31 (BCAP31) (C-Term) antibody (ABIN499417) Western blot analysis of BAP31 in Ramos cell lysate with AP30123PU-N BAP31 antibody a...
Background publications Kojić, Reljin, Reljin: "A neural networks-based hybrid routing protocol for wireless mesh networks." in: Sensors (Basel, Switzerland), Vol. 12, Issue 6, pp. 7548-75, 2012 (PubMed).

Zen, Utech, Liu et al.: "Association of BAP31 with CD11b/CD18. Potential role in intracellular trafficking of CD11b/CD18 in neutrophils." in: The Journal of biological chemistry, Vol. 279, Issue 43, pp. 44924-30, 2004 (PubMed).

Paquet, Cohen-Doyle, Shore et al.: "Bap29/31 influences the intracellular traffic of MHC class I molecules." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 12, pp. 7548-55, 2004 (PubMed).

Ng, Nguyen, Kwan et al.: "p28 Bap31, a Bcl-2/Bcl-XL- and procaspase-8-associated protein in the endoplasmic reticulum." in: The Journal of cell biology, Vol. 139, Issue 2, pp. 327-38, 1997 (PubMed).

Kim, Adachi, Nielsen et al.: "Two new proteins preferentially associated with membrane immunoglobulin D." in: The EMBO journal, Vol. 13, Issue 16, pp. 3793-800, 1994 (PubMed).