Actin, beta (ACTB) (C-Term) antibody

Details for Product No. ABIN499441
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Antigen
Synonyms
ACTA1, A, ACT5C, Ac5C, Act, Act-5C, Act5, Act5c, Actin, Actin/BAP47, Actin5C, BAP47, Bap47, CG4027, Dmel\\CG4027, M32055, T11, act, act 5C, act5C, actin, actin5C, anon-EST:fe2D2, beta-actin, beta-acti ... show more
ACTA1, A, ACT5C, Ac5C, Act, Act-5C, Act5, Act5c, Actin, Actin/BAP47, Actin5C, BAP47, Bap47, CG4027, Dmel\\CG4027, M32055, T11, act, act 5C, act5C, actin, actin5C, anon-EST:fe2D2, beta-actin, beta-actin/Bap47, cyt5C, l(1)G0009, l(1)G0010, l(1)G0025, l(1)G0079, l(1)G0117, l(1)G0177, l(1)G0245, l(1)G0330, l(1)G0420, l(1)G0486, BRWS1, PS1TP5BP1, Actx, E430023M04Rik, Bact, ACT-5, A26C1B, ACTB, POTE2alpha, POTEACTIN, actb, ps1tp5bp1, LOC563571, A26C1A, act-2, B-actin, LOC100136013, LOC100174883, LOC100304816 show less
Epitope
C-Term
(96), (28), (12), (9), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(325), (200), (186), (72), (58), (54), (44), (33), (31), (31), (27), (22), (15), (11), (11), (9), (9), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Host
Rabbit
(205), (130), (19), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(15), (12), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(315), (137), (88), (64), (63), (55), (33), (20), (19), (11), (9), (5), (4), (3), (2), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN499441
Quantity 0.1 mg
Price
401.50 $   Plus shipping costs $45.00
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Immunogen Human b-actin / Beta actin (C-Terminus) Peptide (AP30136CP-N)
Isotype IgG
Specificity Beta-actin antibody was raised against a 16 amino acid peptide from near the carboxy- terminus of human beta-actin.
Purification Affinity chromatography purified via peptide column
Alternative Name Actin beta / ACTB
Background Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism (reviewed in 1). The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging (2). beta actin is one of six different actin isoforms which have been identified. Like GAPDH, Beta-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Alternate names: Actin cytoplasmic 1, Beta-Actin
Gene ID 60
NCBI Accession AAH02409
UniProt P60709
Application Notes ELISA. Western Blot: beta-actin antibody can be used for the detection of beta-actin at 1 – 2μg/ml. Immnocytochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer PBS containing 0.02% sodium azide.
Preservative Sodium azide
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8°C.
Expiry Date 12 months
Background publications Lambrechts, Van Troys, Ampe: "The actin cytoskeleton in normal and pathological cell motility." in: The international journal of biochemistry & cell biology, Vol. 36, Issue 10, pp. 1890-909, 2004 (PubMed).

Gourlay, Ayscough: "The actin cytoskeleton: a key regulator of apoptosis and ageing?" in: Nature reviews. Molecular cell biology, Vol. 6, Issue 7, pp. 583-9, 2005 (PubMed).

Hosts (205), (130), (19), (2)
Reactivities (325), (200), (186), (72), (58), (54), (44), (33), (31), (31), (27), (22), (15), (11), (11), (9), (9), (5), (4), (3), (3), (3), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (315), (137), (88), (64), (63), (55), (33), (20), (19), (11), (9), (5), (4), (3), (2), (1), (1), (1)
Conjugates (15), (12), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1)
Epitopes (96), (28), (12), (9), (4), (4), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1)
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