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CDNF antibody (N-Term)

CDNF Reactivity: Human, Rat, Mouse WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499611
  • Target See all CDNF Antibodies
    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
    Binding Specificity
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 29
    • 12
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 32
    • 7
    • 1
    • 1
    Rabbit
    Clonality
    • 33
    • 8
    Polyclonal
    Conjugate
    • 24
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDNF antibody is un-conjugated
    Application
    • 24
    • 16
    • 13
    • 13
    • 10
    • 10
    • 7
    • 7
    • 5
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to CDNF.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    CDNF antibody was raised against a 12 amino acid peptide from near the amino terminus of human CDNF.
    Isotype
    IgG
    Top Product
    Discover our top product CDNF Primary Antibody
  • Application Notes
    ELISA. Western Blot: CDNF antibody can be used for detection of CDNF at 1 - 2 μg/mL. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    CDNF (Cerebral Dopamine Neurotrophic Factor (CDNF))
    Alternative Name
    CDNF (CDNF Products)
    Synonyms
    ARMETL1 antibody, 9330140G23 antibody, Armetl1 antibody, cerebral dopamine neurotrophic factor antibody, CDNF antibody, Cdnf antibody
    Background
    The conserved dopamine neurotrophic factor (CDNF) is a neurotrophic factor for dopaminergic neurons and highly homologous to the mesencephalic-astrocyte-derived neuro-trophic factor. Somewhat surprisingly, CDCF is expressed at higher levels in tissues such as heart, skeletal muscle and testes than in brain. Similar to the glial cell line-derived neurotrophic factor (GDNF), CDNF can prevent the 6-hydroxylamine (6-OHDA)-induced degeneration of dopaminergic neurons in a rat model of Parkinson's disease. Furthermore, CDNF was able to restore the dopaminergic function and prevent the degeneration of dopaminergic neurons in the substantia nigra, suggesting that CDNF might be suitable for the treatment of Parkinson's disease. At least two isoforms of CDNF are known to exist. This antibody does not cross-react with MANF.Synonyms: ARMET-like protein 1, ARMETL1, Cerebral dopamine neurotrophic factor, Conserved dopamine neurotrophic factor
    Gene ID
    441549
    UniProt
    Q49AH0
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