FEZ2 antibody (Center)

Catalog No. ABIN499834

Product Details anti-FEZ2 Antibody

Target: FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))

Binding Specificity: Center

Reactivity: Rat, Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FEZ2 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Specificity: This antibody reacts to FEZ2.

Purification: Affinity chromatography purified via peptide column

Immunogen: FEZ2 antibody was raised against a 15 amino acid peptide from near the center of human FEZ2.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 0.5 - 1 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for FEZ2

Target: FEZ2 (Fasciculation and Elongation Protein zeta 2 (Zygin II) (FEZ2))

Alternative Name: Zygin-2 (FEZ2 Products)

Synonyms: HUM3CL antibody, 9030616F16 antibody, D17Ertd315e antibody, Zrp antibody, fasciculation and elongation protein zeta 2 antibody, fasciculation and elongation protein zeta 2 (zygin II) antibody, FEZ2 antibody, Fez2 antibody

Background: Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-z substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-z, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-z in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.Synonyms: FEZ2, Fasciculation and elongation protein zeta-2, Zygin II

Gene ID: 9637

NCBI Accession: NP_001036013

UniProt: Q9UHY8