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GDF6 antibody (C-Term)

GDF6 Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499881
  • Target See all GDF6 Antibodies
    GDF6 (Growth Differentiation Factor 6 (GDF6))
    Binding Specificity
    • 15
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 27
    • 19
    • 12
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 30
    • 1
    Rabbit
    Clonality
    • 30
    • 1
    Polyclonal
    Conjugate
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GDF6 antibody is un-conjugated
    Application
    • 31
    • 13
    • 13
    • 9
    • 9
    • 7
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to GDF6.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    GDF6 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human GDF6.
    Isotype
    IgG
    Top Product
    Discover our top product GDF6 Primary Antibody
  • Application Notes
    ELISA. Western Blot: 1 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    GDF6 (Growth Differentiation Factor 6 (GDF6))
    Alternative Name
    BMP13 / GDF6 (GDF6 Products)
    Synonyms
    BMP13 antibody, CDMP2 antibody, KFM antibody, KFS antibody, KFS1 antibody, KFSL antibody, LCA17 antibody, MCOP4 antibody, MCOPCB6 antibody, SCDO4 antibody, SGM1 antibody, GDF16 antibody, gdf16 antibody, CDMP-2 antibody, gdf6 antibody, rdr antibody, sb:cb278 antibody, bmp13 antibody, cdmp2 antibody, gdf-6 antibody, kfs antibody, kfsl antibody, sgm1 antibody, growth differentiation factor 6 antibody, growth differentiation factor 6a antibody, growth differentiation factor 6 S homeolog antibody, GDF6 antibody, Gdf6 antibody, gdf6 antibody, gdf6a antibody, gdf6.S antibody
    Background
    Growth differentiation factors (GDFs) are members of the transforming growth factor (TGF) superfamily that is involved in embryonic development and adult tissue homeostasis. Both GDF6 and GDF7 are closely related to GDF5 which has been shown to induce activation of plasminogen activator, thereby inducing angiogenesis. It is predominantly expressed in long bones during fetal embryonic development and is involved in bone formation. In Xenopus, GDF6 is expressed at the edge of the neural plate and within the anterior neural plate including the eye fields. GDF6 is required for normal formation of some bones and joints in the limbs, skull, and axial skeleton. It may regulate patterning of the ectoderm by interacting with bone morphogenetic proteins (BMPs), and control eye development. Mutations in this gene result in colobomata, which are congenital abnormalities in ocular development, and in Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation.Synonyms: Bone Morphogenetic Protein 13, CDMP2, Cartilage Derived Morphogenetic Protein 2, GDF-16, GDF-6, GDF16
    Gene ID
    392255
    NCBI Accession
    NP_001001557
    UniProt
    Q6KF10
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