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Girdin antibody (C-Term)

CCDC88A Reactivity: Human, Mouse, Rat WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499889
  • Target See all Girdin (CCDC88A) Antibodies
    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
    Binding Specificity
    • 26
    • 15
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 54
    • 15
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 55
    Rabbit
    Clonality
    • 54
    • 1
    Polyclonal
    Conjugate
    • 19
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This Girdin antibody is un-conjugated
    Application
    • 35
    • 17
    • 14
    • 14
    • 14
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    Girdin antibody was raised against a 16 amino acid peptide from near the carboxy terminus human Girdin.
    Isotype
    IgG
    Top Product
    Discover our top product CCDC88A Primary Antibody
  • Application Notes
    ELISA. Western Blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
    Storage Comment
    Store the antibody (in aliquots) at -20 °C.
  • Target
    Girdin (CCDC88A) (Coiled-Coil Domain Containing 88A (CCDC88A))
    Alternative Name
    Girdin (CCDC88A Products)
    Synonyms
    APE antibody, GIRDIN antibody, GIV antibody, GRDN antibody, HkRP1 antibody, KIAA1212 antibody, A430106J12Rik antibody, AI848406 antibody, Ape antibody, C130096N06Rik antibody, C330012F17Rik antibody, D130005J21Rik antibody, Girdin antibody, Giv antibody, Grdn antibody, Hkrp1 antibody, DKFZp459N1815 antibody, RGD1306694 antibody, coiled-coil domain containing 88A antibody, coiled coil domain containing 88A antibody, CCDC88A antibody, Ccdc88a antibody
    Background
    Girdin is a Galpha-interacting protein that can enhance the activation of the protein kinase Akt, remodel the actin cytoskeleton, and is thought to be involved in the regulation of cell migration and cancer metastasis. It has recently been shown that Girdin interacts with Disrupted-in-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders. DISC1 is thought to be involved in the migration, positioning and differentiation of dentate granule cells (DGCs) during development, depletion of Girdin or blocking the Girdin-DISC1 interaction results in defects in axonal sprouting in the CA3 region of the hippocampus and overextended migration of mispositioning of DGCs, suggesting the Girdin plays a role in postnatal neurogenesis in the dentate gyrus.Synonyms: APE, Akt phosphorylation enhancer, CCDC88A, Coiled-coil domain-containing protein 88A, G alpha-interacting vesicle-associated protein, GIV, GRDN, Girders of actin filament, HkRP1, Hook-related protein 1, KIAA1212
    Gene ID
    55704
    NCBI Accession
    NP_060554
    UniProt
    Q3V6T2
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