GRTP1 antibody (N-Term)

Catalog No. ABIN499934

Product Details anti-GRTP1 Antibody

Target: GRTP1 (Growth Hormone Regulated TBC Protein 1 (GRTP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRTP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: GRTP1 antibody was raised against a 18 amino acid peptide from near the amino terminus of human GRTP1.

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 1 - 2 μg/mL. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for GRTP1

Target: GRTP1 (Growth Hormone Regulated TBC Protein 1 (GRTP1))

Alternative Name: GRTP1 / TBC1D6 (GRTP1 Products)

Synonyms: TBC1D6 antibody, LRRGT00052 antibody, grtp1 antibody, zgc:73241 antibody, wu:fd05h02 antibody, MGC84107 antibody, MGC69401 antibody, ADPRHL1 antibody, 5430401C05Rik antibody, C81211 antibody, Tbc1d6 antibody, zgc:112417 antibody, growth hormone regulated TBC protein 1 antibody, growth hormone regulated TBC protein 1a antibody, growth hormone regulated TBC protein 1 S homeolog antibody, GH regulated TBC protein 1 antibody, growth hormone regulated TBC protein 1b antibody, GRTP1 antibody, Grtp1 antibody, grtp1a antibody, grtp1.S antibody, grtp1 antibody, grtp1b antibody

Background: Growth hormone regulated TBC protein 1 (GRTP1) was identified through microarray analysis as a gene whose expression is regulated by growth hormone (GH). It contains the TBC signature motif of GTPase activator proteins of Rab-like small GTPases. GRTP1 mRNA is expressed at highest levels in testes, and is also present in kidney, lung, liver, and intestine. Administration of GH to mice resulted in an increase in GRTP1 mRNA in testes, but a decrease of GRTP1 mRNA in kidney and liver. GRTP1 was identified as an HIV dependency factor (HDF), suggesting that GRTP1 may be an important drug target in HIV treatment. At least three isoforms of GRTP1 are known to exist, this antibody should recognize all isoforms.Synonyms: Growth hormone-regulated TBC protein 1, TBC1 domain family member 6

Gene ID: 79774

UniProt: Q5TC63