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interleukin 23, alpha subunit p19 (IL23A) (C-Term) antibody

Details for Product No. ABIN499996
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Antigen
Synonyms p19, IL-23, IL-23A, IL23P19, P19, SGRF, IL23, il23p19
Epitope
C-Term
(16), (12), (4), (1)
Reactivity
Human, Mouse (Murine)
(69), (46), (14), (1)
Host
Rabbit
(57), (17), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(5), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
(54), (32), (16), (10), (10), (9), (4), (4), (4), (4), (2), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mg
Shipping to United States (Change)
Availability Will be delivered in 6 to 8 Business Days
Catalog No. ABIN499996
401.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23. (AP30418CP-N)
Isotype IgG
Specificity This antibody reacts to IL-23.
Purification Affinity chromatography purified via peptide column
Alternative Name Interleukin-23 alpha / IL23A
Background Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.
Alternate names: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
Gene ID 51561
NCBI Accession AAH66268
UniProt Q9NPF7
Application Notes ELISA. Western BLot: 2 - 4 μg/ml. Immunocytochemistry. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C
Expiry Date 12 months
Background publications Hunter: "New IL-12-family members: IL-23 and IL-27, cytokines with divergent functions." in: Nature reviews. Immunology, Vol. 5, Issue 7, pp. 521-31, 2005 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN499996
401.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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