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IL23A antibody (C-Term)

IL23A Reactivity: Human, Mouse WB, IF, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN499996
  • Target See all IL23A Antibodies
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Binding Specificity
    • 8
    • 7
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 43
    • 18
    • 8
    • 1
    Human, Mouse
    Host
    • 35
    • 8
    • 2
    • 1
    Rabbit
    Clonality
    • 38
    • 8
    Polyclonal
    Conjugate
    • 32
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IL23A antibody is un-conjugated
    Application
    • 31
    • 20
    • 7
    • 7
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Specificity
    This antibody reacts to IL-23.
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.
    Isotype
    IgG
    Top Product
    Discover our top product IL23A Primary Antibody
  • Application Notes
    ELISA. Western BLot: 2 - 4 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
  • Target
    IL23A (Interleukin 23, alpha subunit p19 (IL23A))
    Alternative Name
    Interleukin-23 alpha / IL23A (IL23A Products)
    Synonyms
    IL-23 antibody, IL-23A antibody, IL23P19 antibody, P19 antibody, SGRF antibody, FIL1 antibody, FIL1(ZETA) antibody, FIL1Z antibody, IL-1F7 antibody, IL-1H antibody, IL-1H4 antibody, IL-1RP1 antibody, IL-37 antibody, IL1F7 antibody, IL1H4 antibody, IL1RP1 antibody, p19 antibody, il23p19 antibody, IL23 antibody, interleukin 23 subunit alpha antibody, interleukin 37 antibody, interleukin 23, alpha subunit p19 antibody, IL23A antibody, IL37 antibody, Il23a antibody
    Background
    Like interleukin-27 (IL-27), IL-23 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines. It exists as a heterodimer composed of the IL-12p40 subunit and a novel p19 subunit. IL-23 is secreted by activated dendritic cells, macrophages, and monocytes. Its biological activities include enhancing the proliferation of memory T cells and the production of IFN-gamma, IL-12, and TNF-alpha from activated T cells, and can stimulate macrophages to produce TNF-alpha and nitric oxide. It has also been shown to possess potent anti-tumor and anti-metastatic activity in mouse models of cancer, suggesting a potential role for IL-23 in therapeutic treatment of cancer.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
    Gene ID
    51561
    UniProt
    Q9NPF7
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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