IL32 antibody (Intermediate Domain)

Catalog No. ABIN500010

Product Details anti-IL32 Antibody

Target: IL32 (Interleukin 32 (IL32))

Binding Specificity: Intermediate Domain

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL32 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: IL-32 antibody was raised against a 16 amino acid peptide from near the center of human IL-32.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human IL-32 (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 2.5 - 5 μg/mL. This antibody detects the largest isoform of IL-32.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for IL32

Target: IL32 (Interleukin 32 (IL32))

Alternative Name: Interleukin-32 / IL32 (IL32 Products)

Synonyms: IL-32alpha antibody, IL-32beta antibody, IL-32delta antibody, IL-32gamma antibody, NK4 antibody, TAIF antibody, TAIFa antibody, TAIFb antibody, TAIFc antibody, TAIFd antibody, interleukin 32 antibody, IL32 antibody

Background: Interleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2 . It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32 (2). IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-alpha, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFNgamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis (3).Synonyms: IL-32, NK4, Natural killer cells protein 4, TAIF, Tumor necrosis factor alpha-inducing factor

Gene ID: 9235

UniProt: P24001