STRADB antibody (Intermediate Domain)

Catalog No. ABIN500022

Product Details anti-STRADB Antibody

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Binding Specificity: Intermediate Domain

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This STRADB antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: ILPIP antibody was raised against a synthetic peptide corresponding to amino acids near the center of human ILPIP.

Purification: Affinity chromatography purified via peptide column

Immunogen: Human ILPIP (Intermediate Domain) Peptide

Isotype: IgG

Application Details

Application Notes: ELISA. Western Blot: 1 to 2 μg/mL. A 34 kDa band can be detected with positive control. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for STRADB

Target: STRADB (STE20-Related Kinase Adaptor beta (STRADB))

Alternative Name: STRAD beta / ILPIP (STRADB Products)

Synonyms: Als2cr2 antibody, RGD1559449 antibody, als2cr2 antibody, MGC82468 antibody, STRADB antibody, ALS2CR2 antibody, AA792893 antibody, B830008M19 antibody, D1Ucla2 antibody, ILPIP antibody, ILPIPA antibody, PRO1038 antibody, Papk antibody, Syradb antibody, CALS-21 antibody, PAPK antibody, STE20-related kinase adaptor beta antibody, STE20-related kinase adaptor beta L homeolog antibody, Stradb antibody, STRADB antibody, stradb.L antibody

Background: ILPIP (ILP-interacting protein) has recently been shown to interact with XIAP, a member of the IAP (Inhibitor of Apoptosis) protein family (1). Together, these two proteins synergistically activate the TAK1/JNK1 signal transduction pathway, which acts to protect against the interleukin-1? converting enzyme of Fas-induced apotosis (1,2). This protein was independently isolated and characterized as polyploidy-associated protein kinase (PAPK), a member of the Ste20/germinal center kinase family that modulates cytoskeletal organization and cell survival (3), suggesting that its protective role may be a function of its kinase activity. Although two mRNA sequences have been isolated, only the shorter isoform has been observed.Synonyms: ALS2CR2, CALS-21, PRO1038, Pseudokinase ALS2CR2, STE20-related kinase adapter protein beta, STRADB

Gene ID: 55437

NCBI Accession: NP_061041

UniProt: Q9C0K7

Pathways: AMPK Signaling